Últimos itens adicionados do Acervo: Biblioteca Digital da Produção Intelectual e Científica da Unicamp

A Biblioteca Digital da Produção Intelectual e Científica da Unicamp tem por objetivo reunir e disseminar a produção intelectual, acadêmica e cultural da universidade e preservar sua memória institucional, além de contribuir para ampliar a visibilidade da instituição e dos seus pesquisadores em âmbito nacional e internacional.

Página 14 dos resultados de 1947 itens digitais encontrados em 0.002 segundos

‣ Transcriptional Regulation of the Lignin Biosynthetic Pathway Revisited: New Players and Insights

Grima-Pettenati, Jacqueline; Soler, Marcal; Camargo, Eduardo Leal O.; Wang, Hua
Fonte: Elsevier; San Diego Publicador: Elsevier; San Diego
Tipo: Artigo de Revista Científica
Português
The discovery that AC elements coordinated the regulation of genes belonging to the entire lignin biosynthetic pathway was the first breakthrough in understanding how lignin biosynthesis is regulated. Since then, tremendous progress has been made in the identification and characterization of many transcription factors (TFs) that regulate the genes of the phenylpropanoid branch pathway leading to lignin. A major breakthrough consisted in the discovery of a hierarchical transcriptional network regulating the biosynthesis of lignified secondary walls (SWs) in Arabidopsis. The NAC TFs (VND/NST/SND) work as the first layer of master switches activating the whole SW biosynthetic network through the regulation of a cascade of downstream TFs. Among these, MYB46/83 act as a second layer of master switches. Recent findings, however, reveal that the regulation of SW formation is far more complex than initially thought, involving both positive and negative regulators, dual function regulators, feedback loops, combinatorial complexes and cross talk between pathways. Finally, because of the great potential that lignocellulosic biomass represents for the production of bioenergy, there is a great interest in further elucidating the molecular mechanisms underlying the regulation of lignified SW and subsequently applying this knowledge to improve their saccharification potential for the generation of biofuels.

‣ Prevalence of Avian Pathogenic Escherichia coli (APEC) Clone Harboring sfa Gene in Brazil

Knoebl, Terezinha; Moreno, Andrea Micke; Paixao, Renata; Tardelli Gomes, Tania Aparecida; Midolli Vieira, Monica Aparecida; da Silva Leite, Domingos; Blanco, Jesus E.; Piantino Ferreira, Antonio Jose
Fonte: Hindawi Publishing Corporation; New York Publicador: Hindawi Publishing Corporation; New York
Tipo: Artigo de Revista Científica
Português
Escherichia coli sfa+ strains isolated from poultry were serotyped and characterized by polymerase chain reaction (PCR) and amplified fragment length polymorphism (AFLP). Isolates collected from 12 Brazilian poultry farms mostly belonged to serogroup O6, followed by serogroups O2, O8, O21, O46, O78, O88, O106, O111, and O143. Virulence genes associated were: iuc 90%, fim 86% neuS 60%, hly 34%, tsh 28%, crl/csg 26%, iss 26%, pap 18%, and 14% cnf. Strains from the same farmpresented more than one genotypic pattern belonging to different profiles in AFLP. AFLP showed a clonal relation between Escherichia coli sfa+ serogroup O6. The virulence genes found in these strains reveal some similarity with extraintestinal E. coli (ExPEC), thus alerting for potential zoonotic risk.; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

‣ Genetic transformation of Citrus sinensis with Citrus tristeza virus (CTV) derived sequences and reaction of transgenic lines to CTV infection

Muniz, F. R.; De Souza, A. J.; Stipp, L. C. L.; Schinor, E.; Freitas, W., Jr.; Harakava, R.; Stach-Machado, D. R.; Rezende, J. A. M.; Mourao Filho, F. A. A.; Mendes, B. M. J.
Fonte: Springer; Dordrecht Publicador: Springer; Dordrecht
Tipo: Artigo de Revista Científica
Português
Transgenic Citrus sinensis (L.) Osb. plants, cvs. Valencia and Hamlin, expressing Citrus tristeza virus (CTV) derived sequences were obtained by genetic transformation. The gene constructs were pCTV-CP containing the 25 kDa major capsid protein gene (CTV-CP), pCTV-dsCP containing the same CTV-CP gene in an intron-spliced hairpin construct, and pCTV-CS containing a 559 nt conserved region of the CTV genome. The transgenic lines were identified by PCR and the transgene integration was confirmed by Southern blot. Transgene mRNA could be detected in most transgenic lines containing pCTV-CP or pCTV-CS transgene. The mRNA of pCTV-dsCP transgene was almost undetectable, with very light bands in most analyzed plants. The transgene transcription appears to be closely linked to the type of gene construct. The virus challenge assays reveals that all transgenic lines were infected. However, it was possible to identify propagated clones of transgenic plants of both cultivars studied with a low virus titer, with values similar to the non-inoculated plants (negative control). These results suggested that the transgenic plants present some level of resistance to virus replication. The higher number of clones with low virus titer and where mRNA could not be detected or was presented in a very light band was found for pCTV-dsCP-derived transgenic lines.; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

‣ Population and comparative genomics of the amphibian pathogen Batrachochytrium dendrobatidis reveal history of an emerging infectious disease

Rosenblum, E. B.; James, T. Y.; Zamudio, K. Kelly; Poorten, T. J.; Rodriguez, D.; Illut, D.; Toledo, F.; Arellano, M. L.; Tovar, E. Medina; Richards-Hrdlicka, K.; Joneson, S.; Longcore, J.; Stajich, J. E.
Fonte: Wiley-Blackwell; Hoboken Publicador: Wiley-Blackwell; Hoboken
Tipo: Artigo de Revista Científica
Português

‣ Germination and seedling morphology of four South American Smilax (Smilacaceae)

Martins, Aline Redondo; Soares, Anielca Nascimento; Bombo, Aline Bertolosi; Fidelis, Alessandra; da Luz Coelho Novembre, Ana Dionisia; da Gloria, Beatriz Appezzato
Fonte: Revista De Biologia Tropical; San Jose Publicador: Revista De Biologia Tropical; San Jose
Tipo: Artigo de Revista Científica
Português
Species of Smilax,, also known as greenbrier, are widely distributed in Brazil and their commercial trades are carried out by the extractivism of native species. We the aim to provide information about the germination and development of seedlings in four Smilax species, different experiments were developed under controlled conditions. We evaluated two germination treatments: temperature (30 degrees C and 20-30 degrees C) and light (presence/absence), and for few cases the tetrazolium treatment was applied. A different treatment response was observed among the studied species. Light had a significant influence in S. brasiliensis, with the highest germination rates at 20-30 C in dark conditions. S. campestris showed significant differences among temperature treatments, but not to light; while S. cissoides showed high germination rates (66-78%), independently of treatment. However, S. polyantha had low germination rates (19-24%). After one year, the expanded leaves showed different characteristics among the studied species. Leaves of S. brasiliensis were ovate, coriaceous, three main veins and prickle-like structures only on the midrib on abaxial face. S. campestris leaves were oblong, coriaceous and prickle-like structures were located at the leaf midrib and margin. S. cissoides had ovate-elliptic...

‣ Proteomic analysis of rat skeletal muscle submitted to one bout of incremental exercise

Gandra, P. G.; Valente, R. H.; Perales, J.; Pacheco, A. G.; Macedo, D. V.
Fonte: Wiley-Blackwell; Hoboken Publicador: Wiley-Blackwell; Hoboken
Tipo: Artigo de Revista Científica
Português
Exercise can alter gene transcriptional and protein translational rates leading to changes in protein abundance toward adaptation to exercise. We investigated the alterations in protein abundance in skeletal muscle after one bout of an exhaustive exercise through proteomic analysis. Gastrocnemius muscles were sampled from non-exercised control rats and from rats exercised on a treadmill with incremental increases in speed until exhaustion (approximately 30 min). Rats were sacrificed 3 and 24 h after exercise cessation. Two-dimensional gel electrophoresis was performed and spots with a significant alteration in relative volume were identified by mass spectrometry. Six spots presented statistically significant altered abundances after exercise. The spots identified as the metabolic related proteins triosephosphate isomerase 1, glyceraldehyde-3-phosphate dehydrogenase, the beta subunit of pyruvate dehydrogenase E1 and carnitine palmitoyltransferase 2 were all more abundant after exercise. One spot identified as heat shock cognate 70 was also more abundant after exercise. One spot demonstrated a decreased abundance after exercise and was identified as a-actin. These results suggest that a single session of exhaustive incremental exercise in untrained muscle can alter thin filaments synthesis/degradation rate and enhance cytosolic and mitochondrial proteins synthesis. The identified proteins may be important to a general preconditioning of skeletal muscle for subsequent exercise sessions.; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

‣ A mixed model QTL analysis for sugarcane multiple-harvest-location trial data

Pastina, M. M.; Malosetti, M.; Gazaffi, R.; Mollinari, M.; Margarido, G. R. A.; Oliveira, K. M.; Pinto, L. R.; Souza, A. P.; van Eeuwijk, F. A.; Garcia, A. A. F.
Fonte: Springer; New York Publicador: Springer; New York
Tipo: Artigo de Revista Científica
Português
Sugarcane-breeding programs take at least 12 years to develop new commercial cultivars. Molecular markers offer a possibility to study the genetic architecture of quantitative traits in sugarcane, and they may be used in marker-assisted selection to speed up artificial selection. Although the performance of sugarcane progenies in breeding programs are commonly evaluated across a range of locations and harvest years, many of the QTL detection methods ignore two- and three-way interactions between QTL, harvest, and location. In this work, a strategy for QTL detection in multi-harvest-location trial data, based on interval mapping and mixed models, is proposed and applied to map QTL effects on a segregating progeny from a biparental cross of pre-commercial Brazilian cultivars, evaluated at two locations and three consecutive harvest years for cane yield (tonnes per hectare), sugar yield (tonnes per hectare), fiber percent, and sucrose content. In the mixed model, we have included appropriate (co)variance structures for modeling heterogeneity and correlation of genetic effects and non-genetic residual effects. Forty-six QTLs were found: 13 QTLs for cane yield, 14 for sugar yield, 11 for fiber percent, and 8 for sucrose content. In addition...

‣ A novel protein refolding protocol for the solubilization and purification of recombinant peptidoglycan-associated lipoprotein from Xylella fastidiosa overexpressed in Escherichia coil

Santos, Clelton A.; Beloti, Lilian L.; Toledo, Marcelo A. S.; Crucello, Aline; Favaro, Marianna T. P.; Mendes, Juliano S.; Santiago, Andre S.; Azzoni, Adriano R.; Souza, Anete P.
Fonte: Elsevier; San Diego Publicador: Elsevier; San Diego
Tipo: Artigo de Revista Científica
Português
Xylella fastidiosa is a Gram-negative xylem-limited plant pathogenic bacterium responsible for several economically important crop diseases. Here, we present a novel and efficient protein refolding protocol for the solubilization and purification of recombinant X. fastidiosa peptidoglycan-associated lipoprotein (XfPal). Pal is an outer membrane protein that plays important roles in maintaining the integrity of the cell envelope and in bacterial pathogenicity. Because Pal has a highly hydrophobic N-terminal domain, the heterologous expression studies necessary for structural and functional protein characterization are laborious once the recombinant protein is present in inclusion bodies. Our protocol based on the denaturation of the XfPal-enriched inclusion bodies with 8 M urea followed by buffer-exchange steps via dialysis proved effective for the solubilization and subsequent purification of XfPal, allowing us to obtain a large amount of relatively pure and folded protein. In addition, XfPal was biochemically and functionally characterized. The method for purification reported herein is valuable for further research on the three-dimensional structure and function of Pal and other outer membrane proteins and can contribute to a better understanding of the role of these proteins in bacterial pathogenicity...

‣ Functional and structural studies of the disulfide isomerase DsbC from the plant pathogen Xylella fastidiosa reveals a redox-dependent oligomeric modulation in vitro

Santos, Clelton A.; Toledo, Marcelo A. S.; Trivella, Daniela B. B.; Beloti, Lilian L.; Schneider, Dilaine R. S.; Saraiva, Antonio M.; Crucello, Aline; Azzoni, Adriano R.; Souza, Alessandra A.; Aparicio, Ricardo; Souza, Anete P.
Fonte: Wiley-Blackwell; Hoboken Publicador: Wiley-Blackwell; Hoboken
Tipo: Artigo de Revista Científica
Português
Xylella fastidiosa is a Gram-negative bacterium that grows as a biofilm inside the xylem vessels of susceptible plants and causes several economically relevant crop diseases. In the present study, we report the functional and low-resolution structural characterization of the X. fastidiosa disulfide isomerase DsbC (XfDsbC). DsbC is part of the disulfide bond reduction/isomerization pathway in the bacterial periplasm and plays an important role in oxidative protein folding. In the present study, we demonstrate the presence of XfDsbC during different stages of X. fastidiosa biofilm development. XfDsbC was not detected during X. fastidiosa planktonic growth; however, after administering a sublethal copper shock, we observed an overexpression of XfDsbC that also occurred during planktonic growth. These results suggest that X. fastidiosa can use XfDsbC in vivo under oxidative stress conditions similar to those induced by copper. In addition, using dynamic light scattering and small-angle X-ray scattering, we observed that the oligomeric state of XfDsbC in vitro may be dependent on the redox environment. Under reducing conditions, XfDsbC is present as a dimer, whereas a putative tetrameric form was observed under nonreducing conditions. Taken together...

‣ CHARACTERIZATION OF RALSTONIA SOLANACEARUM STRAINS FROM BRAZIL USING MOLECULAR METHODS AND PATHOGENICITY TESTS

Rodrigues, L. M. R.; Destefano, S. A. L.; da Silva, M. J.; Costa, G. G. L.; Maringoni, A. C.
Fonte: Edizioni Ets; Pisa Publicador: Edizioni Ets; Pisa
Tipo: Artigo de Revista Científica
Português
Forty one Brazilian strains of Ralstonia solanacearum from ornamental plants (Begonia sp., Fuchsia sp., Oxalis sp., Pelargonium x hortorum and Tagetes sp.), eucalyptus (Eucalyptus sp.), Solanaceae (Nicotiana tabacum, Solanum jilo, S. lycopersicum, S. melon gena, S. tuberosum), banana (Musa sp.) and heliconia (Heliconia sp.), belonging to three different races and five biovars, were characterized by ERIC and BOX-PCR and classified in phylotypes by sequence analysis of the endoglucanase (Egl) and MutS genes. The virulence of 22 strains was evaluated on tomato cv. Petomech VF, potato cv. Agata and tobacco var. Burley. In the ERIC and BOX-PCR analysis, strains were separated into two main clusters showing high genetic diversity among them, with no correlation concerning race, biovar or geographical origin. Phylogenetic analysis based on sequences of part of the Egl and MutS genes revealed the predominance of phylotype II in Brazil. With exception of strains belonging to race 2, which were not included in the experiments, pathogenicity tests carried out with different strains of R. solanacearum showed high virulence on tomato and potato, and lower virulence on tobacco, showing no relationship with race, biovar or host plant from which the tested strain were originally isolated.; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

‣ Azimuthal Charged-Particle Correlations and Possible Local Strong Parity Violation

ABELEV, B. I.; AGGARWAL, M. M.; AHAMMED, Z.; ALAKHVERDYANTS, A. V.; ANDERSON, B. D.; ARKHIPKIN, D.; AVERICHEV, G. S.; BALEWSKI, J.; BARANNIKOVA, O.; BARNBY, L. S.; BAUMGART, S.; BEAVIS, D. R.; BELLWIED, R.; BENEDOSSO, F.; BETANCOURT, M. J.; BETTS, R. R.;
Fonte: AMER PHYSICAL SOC Publicador: AMER PHYSICAL SOC
Tipo: Artigo de Revista Científica
Português
Parity-odd domains, corresponding to nontrivial topological solutions of the QCD vacuum, might be created during relativistic heavy-ion collisions. These domains are predicted to lead to charge separation of quarks along the system's orbital momentum axis. We investigate a three-particle azimuthal correlator which is a P even observable, but directly sensitive to the charge separation effect. We report measurements of charged hadrons near center-of-mass rapidity with this observable in Au+Au and Cu+Cu collisions at s(NN)=200 GeV using the STAR detector. A signal consistent with several expectations from the theory is detected. We discuss possible contributions from other effects that are not related to parity violation.; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

‣ Longitudinal double-spin asymmetry and cross section for inclusive neutral pion production at midrapidity in polarized proton collisions at s=200 GeV

ABELEV, B. I.; AGGARWAL, M. M.; AHAMMED, Z.; ALAKHVERDYANTS, A. V.; ANDERSON, B. D.; ARKHIPKIN, D.; AVERICHEV, G. S.; BALEWSKI, J.; BARANNIKOVA, O.; BARNBY, L. S.; BAUMGART, S.; BEAVIS, D. R.; BELLWIED, R.; BENEDOSSO, F.; BETANCOURT, M. J.; BETTS, R. R.;
Fonte: AMER PHYSICAL SOC Publicador: AMER PHYSICAL SOC
Tipo: Artigo de Revista Científica
Português
We report a measurement of the longitudinal double-spin asymmetry A(LL) and the differential cross section for inclusive pi(0) production at midrapidity in polarized proton collisions at s=200 GeV. The cross section was measured over a transverse momentum range of 1 < p(T)< 17 GeV/c and found to be in good agreement with a next-to-leading order perturbative QCD calculation. The longitudinal double-spin asymmetry was measured in the range of 3.7 < p(T)< 11 GeV/c and excludes a maximal positive gluon polarization in the proton. The mean transverse momentum fraction of pi(0)'s in their parent jets was found to be around 0.7 for electromagnetically triggered events.; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

‣ Measurement of the Depth of Maximum of Extensive Air Showers above 10(18) eV

ABRAHAM, J.; ABREU, P.; AGLIETTA, M.; AHN, E. J.; ALLARD, D.; ALLEKOTTE, I.; ALLEN, J.; ALVAREZ-MUNIZ, J.; AMBROSIO, M.; ANCHORDOQUI, L.; ANDRINGA, S.; ANTICIC, T.; ANZALONE, A.; ARAMO, C.; ARGANDA, E.; ARISAKA, K.; ARQUEROS, F.; ASOREY, H.; ASSIS, P.; AU
Fonte: AMER PHYSICAL SOC Publicador: AMER PHYSICAL SOC
Tipo: Artigo de Revista Científica
Português
We describe the measurement of the depth of maximum, X(max), of the longitudinal development of air showers induced by cosmic rays. Almost 4000 events above 10(18) eV observed by the fluorescence detector of the Pierre Auger Observatory in coincidence with at least one surface detector station are selected for the analysis. The average shower maximum was found to evolve with energy at a rate of (106 +/- 35-21) g/cm(2)/decade below 10(18.24) +/- (0.05) eV, and d24 +/- 3 g/cm(2)/ecade above this energy. The measured shower-to-shower fluctuations decrease from about 55 to 26 g/cm(2). The interpretation of these results in terms of the cosmic ray mass composition is briefly discussed.

‣ Limit on the diffuse flux of ultrahigh energy tau neutrinos with the surface detector of the Pierre Auger Observatory

ABRAHAM, J.; ABREU, P.; AGLIETTA, M.; AGUIRRE, C.; AHN, E. J.; ALLARD, D.; ALLEKOTTE, I.; ALLEN, J.; ALLISON, P.; ALVAREZ-MUNIZ, J.; AMBROSIO, M.; ANCHORDOQUI, L.; ANDRINGA, S.; ANZALONE, A.; ARAMO, C.; ARGIRO, S.; ARISAKA, K.; ARNEODO, F.; ARQUEROS, F.;
Fonte: AMER PHYSICAL SOC Publicador: AMER PHYSICAL SOC
Tipo: Artigo de Revista Científica
Português
Data collected at the Pierre Auger Observatory are used to establish an upper limit on the diffuse flux of tau neutrinos in the cosmic radiation. Earth-skimming nu(tau) may interact in the Earth's crust and produce a tau lepton by means of charged-current interactions. The tau lepton may emerge from the Earth and decay in the atmosphere to produce a nearly horizontal shower with a typical signature, a persistent electromagnetic component even at very large atmospheric depths. The search procedure to select events induced by tau decays against the background of normal showers induced by cosmic rays is described. The method used to compute the exposure for a detector continuously growing with time is detailed. Systematic uncertainties in the exposure from the detector, the analysis, and the involved physics are discussed. No tau neutrino candidates have been found. For neutrinos in the energy range 2x10(17) eV < E(nu)< 2x10(19) eV, assuming a diffuse spectrum of the form E(nu)(-2), data collected between 1 January 2004 and 30 April 2008 yield a 90% confidence-level upper limit of E(nu)(2)dN(nu tau)/dE(nu)< 9x10(-8) GeV cm(-2) s(-1) sr(-1).

‣ Psychogenetics of Turner syndrome: an investigation of 28 subjects and respective controls using the Bender test and Piagetian scales

RICARDI, F. C. F.; ZAIA, L. L.; PELLEGRINO-ROSA, I.; ROSA, J. T.; ASSIS, O. Z. Mantovani de; SALDANHA, P. H.
Fonte: FUNPEC-EDITORA Publicador: FUNPEC-EDITORA
Tipo: Artigo de Revista Científica
Português
Piagetian scales and the Bender visual motor gestalt test (BT) were applied to 28 subjects with universal 45, X Turner syndrome (TS), and their respective controls, in order to investigate their cognitive performance. Dermatoglyphics were also analyzed to obtain clues concerning embryological changes that may have appeared during development of the nervous system and could be associated with cognitive performance of TS patients. Dermatoglyphic pattern distribution was similar to that reported in previous studies of TS individuals: ulnar loops in the digital patterns and finger ridge, a-b, and A'-d counts were more frequent, while arch and whorl patterns were less frequent compared to controls. However, we did not find higher frequencies of hypothenar pattern, maximum atd angle, and ulnarity index in our TS subjects, unlike other investigations. Furthermore, we found significant differences between TS and control T line index values. The BT scores were also lower in probands, as has been previously reported, revealing a neurocognitive deficit of visual motor perception in TS individuals, which could be due to an absence of, or deficiency in, cerebral hemispheric lateralization. However, TS subjects seemed to improve their performance on BT with age. Cognitive performance of the TS subjects was not significantly different from that of controls...

‣ Insulin and leptin relations in obesity: a multimedia approach

YOKAICHIYA, Daniela K.; GALEMBECK, Eduardo; TORRES, Bayardo B.; SILVA, Jose Antonio Da; ARAUJO, Daniele R. de
Fonte: AMER PHYSIOLOGICAL SOC Publicador: AMER PHYSIOLOGICAL SOC
Tipo: Artigo de Revista Científica
Português
Obesity has been recognized as a worldwide public health problem. It significantly increases the chances of developing several diseases, including Type II diabetes. The roles of insulin and leptin in obesity involve reactions that can be better understood when they are presented step by step. The aim of this work was to design software with data from some of the most recent publications on obesity, especially those concerning the roles of insulin and leptin in this metabolic disturbance. The most notable characteristic of this software is the use of animations representing the cellular response together with the presentation of recently discovered mechanisms on the participation of insulin and leptin in processes leading to obesity. The software was field tested in the Biochemistry of Nutrition web-based course. After using the software and discussing its contents in chatrooms, students were asked to answer an evaluation survey about the whole activity and the usefulness of the software within the learning process. The teaching assistants (TA) evaluated the software as a tool to help in the teaching process. The students' and TAs' satisfaction was very evident and encouraged us to move forward with the software development and to improve the use of this kind of educational tool in biochemistry classes.; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

‣ The ethical dimension f analyst's interventions facing institutional demands of CAPS

Dassoler, Volnei Antonio; de Sousa Palma, Claudia Maria
Fonte: Assoc Univ Pequisa Psicopatologia Fundamental; Sao Paulo Publicador: Assoc Univ Pequisa Psicopatologia Fundamental; Sao Paulo
Tipo: Artigo de Revista Científica
Português
(The ethical dimension f analyst's interventions facing institutional demands of CAPS) Considering the complexities involved in setting up clinical work in the psychosocial field, analyst must question their own contributions toward improvements in this area. This issue is presented here as a considerable challenge, due to the limitations of psychoanalytic practice and, especially, the differences between conventional clinical practice and that carried out in institutional and political settings. From this perspective, we call attention to the notion of ethics as a differentiating and guiding concept for psychoanalytic practice in its contribution toward the treatment provided at CAPS.

‣ Relationships between gender, age, family conditions, physical and mental health, and social isolation of elderly caregivers

Neri, Anita Liberalesso; Yassuda, Monica Sanches; Garofe Fortes-Burgos, Andrea Cristina; Mantovani, Efigenia Passarelli; Arbex, Flavia Silva; de Souza Torres, Stella Vidal; Perracini, Monica Rodrigues; Guariento, Maria Elena
Fonte: Cambridge Univ Press; New York Publicador: Cambridge Univ Press; New York
Tipo: Artigo de Revista Científica
Português
Background: In an aging population an increasing number of elderly caregivers will be called upon to provide care over a long period, during which time they will be burdened both by caregiving and by the physiological effects of their own aging. Among them there will be more aged male caregivers, who will probably be less prepared than women to become caregivers. The aim of this study was to investigate the relationship between caregivers' gender, age, family income, living arrangements and social support as independent variables, and depressive symptoms, comorbidities, level of frailty, grip strength, walking speed and social isolation, as dependent variables. Methods: 176 elderly people (123 women) were selected from a sample of a population-based study on frailty (n = 900), who had cared for a spouse (79.3%) and/or parents (31.4%) in the past five years (mean age = 71.8 +/- 4.86 years; mean monthly family income in minimum wages = 4.64 +/- 5.14). The study used questionnaires and self-report scales, grip strength and walking speed tests. Results: 65% of participants evaluated caregiving as being very stressful. Univariate analyses of regression showed low family income as a risk factor for depression; being female and low perceived social support as a risk for comorbidities; being 80 years of age and above for low grip strength; and being male for social isolation indicated by discontinuity of activities and social roles. In multivariate analyses of regression...

‣ PSYCHOLOGICAL MEANINGS OF TAKING CARE OF FATHER'S/MOTHER'S BODY OF THE OPPOSITE SEX AS REPORTED BY BRAZILIAN SON/DAUGHTER OF PATIENTS WITH DEMENTIA: A QUALITATIVE STUDY

Perugini, T. R.; Turato, E. R.
Fonte: Elsevier; Paris Publicador: Elsevier; Paris
Tipo: Artigo de Revista Científica
Português

‣ The role of delays in severe maternal morbidity and mortality: expanding the conceptual framework

Pacagnella, Rodolfo Carvalho; Cecatti, Jose Guilherme; Osis, Maria Jose; Souza, Joao Paulo
Fonte: Elsevier; Amsterdam Publicador: Elsevier; Amsterdam
Tipo: Artigo de Revista Científica
Português
Maternal mortality has gained importance in research and policy since the mid-1980s. Thaddeus and Maine recognized early on that timely and adequate treatment for obstetric complications were a major factor in reducing maternal deaths. Their work offered a new approach to examining maternal mortality, using a three-phase framework to understand the gaps in access to adequate management of obstetric emergencies: phase I - delay in deciding to seek care by the woman and/or her family; phase II - delay in reaching an adequate health care facility; and phase III - delay in receiving adequate care at that facility. Recently, efforts have been made to strengthen health systems' ability to identify complications that lead to maternal deaths more rapidly. This article shows that the combination of the "three delays" framework with the maternal "near-miss" approach, and using a range of information-gathering methods, may offer an additional means of recognizing a critical event around childbirth. This approach can be a powerful tool for policymakers and health managers to guarantee the principles of human rights within the context of maternal health care, by highlighting the weaknesses of systems and obstetric services. (C) 2012 Reproductive Health Matters