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‣ The Effects of Continuous Positive Airway Pressure on Prehypertension and Masked Hypertension in Men With Severe Obstructive Sleep Apnea

DRAGER, Luciano F.; PEDROSA, Rodrigo P.; DINIZ, Patricia M.; DIEGUES-SILVA, Luzia; MARCONDES, Bianca; COUTO, Roberta B.; GIORGI, Dante M. A.; KRIEGER, Eduardo M.; LORENZI-FILHO, Geraldo
Fonte: LIPPINCOTT WILLIAMS & WILKINS Publicador: LIPPINCOTT WILLIAMS & WILKINS
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
37.630776%
Obstructive sleep apnea and hypertension are common conditions that frequently coexist. Continuous positive airway pressure (CPAP) reduces blood pressure in patients with obstructive sleep apnea and sustained hypertension. However, the impact of CPAP on patients with obstructive sleep apnea and prehypertension and masked hypertension, conditions associated with increased cardiovascular risk, is unknown. Thirty-six male patients (age, 43 +/- 7 years; body mass index, 28.8 +/- 3.0 kg/m(2)) with untreated severe obstructive sleep apnea (apnea-hypopnea index, 56 +/- 22 events/hr on polysomnography) with diagnostic criteria for prehypertension and/or masked hypertension, based on office and 24-hour ambulatory blood pressure monitoring, respectively, were studied. The patients randomized to no treatment (control; n=18) or CPAP (n=18) for 3 months had similar frequency of prehypertension and masked hypertension at study entry. There were no significant changes in blood pressure in patients randomized to the control group. In contrast, patients randomized to CPAP presented significant reduction in office systolic (from 126 +/- 5 to 121 +/- 7 mm Hg; P=0.001) and a trend for diastolic blood pressure (from 75 +/- 7 to 73 +/- 8 mm Hg; P=0.08) as well as a significant decrease in daytime and nighttime systolic and diastolic blood pressure (P < 0.05 for each comparison). There was a significant reduction in the frequency of prehypertension (from 94% to 55%; P=0.02) and masked hypertension (from 39% to 5%; P=0.04) only in the CPAP group. In conclusion...

‣ Variation in Body Composition Determines Long-Term Blood Pressure Changes in Pre-Hypertension The MONICA/KORA (Monitoring Trends and Determinants on Cardiovascular Diseases/Cooperative Research in the Region of Augsburg) Cohort Study

MARKUS, Marcello Ricardo Paulista; STRITZKE, Jan; SIEWERT, Ulrike; LIEB, Wolfgang; LUCHNER, Andreas; DOERING, Angela; KEIL, Ulrich; HENSE, Hans-Werner; SCHUNKERT, Heribert; MONICA KORA Investigators
Fonte: ELSEVIER SCIENCE INC Publicador: ELSEVIER SCIENCE INC
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
37.574133%
Objectives We studied the relationship between changes in body composition and changes in blood pressure levels. Background The mechanisms underlying the frequently observed progression from pre-hypertension to hypertension are poorly understood. Methods We examined 1,145 subjects from a population-based survey at baseline in 1994/1995 and at follow-up in 2004/2005. First, we studied individuals pre-hypertensive at baseline who, during 10 years of follow-up, either had normalized blood pressure (PreNorm, n = 48), persistently had pre-hypertension (PrePre, n = 134), or showed progression to hypertension (PreHyp, n = 183). In parallel, we studied predictors for changes in blood pressure category in individuals hypertensive at baseline (n = 429). Results After 10 years, the PreHyp group was characterized by a marked increase in body weight (+5.71% [95% confidence interval (CI): 4.60% to 6.83%]) that was largely the result of an increase in fat mass (+17.8% [95% CI: 14.5% to 21.0%]). In the PrePre group, both the increases in body weight (+1.95% [95% CI: 0.68% to 3.22%]) and fat mass (+8.09% [95% CI: 4.42% to 11.7%]) were significantly less pronounced than in the PreHyp group (p < 0.001 for both). The PreNorm group showed no significant change in body weight (-1.55% [95% CI: -3.70% to 0.61%]) and fat mass (+0.20% [95% CI: -6.13% to 6.52%]...

‣ Estudo dos polimorfismos do gene DUFFY em pacientes com hipertensão maligna e doadores de sangue; Duffy gene polymorphism study in patients with malignant hypertension and blood donors

Pagliarini, Thiago
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 07/08/2008 Português
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A hipertensão essencial tem alta prevalência mundial, bem como, causas genéticas e ambientais. Na busca de correlações genéticas para a hipertensão, foi descrito um potencial papel do DARC (Duffy Antigen Receptor of Chemokines) como receptor de Interleucina-8 em endotélio e que essa interação poderia contribuir para a patogênese da pré-eclampsia. O DARC está expresso em vários tecidos além da linhagem eritróide, em especial nas células endoteliais. A glicoproteína DARC carreia determinantes antigênicos e também é receptora para Plasmodium vivax, tendo relevância biológica significante. Esse estudo teve como objetivo estudar a freqüência fenotípica e genotípica do Sistema de Grupo Sangüíneo Duffy comparando pacientes com hipertensão maligna com doadores de sangue normotensos. Foram estudadas 43 amostras de sangue de pacientes com diagnóstico de hipertensão maligna da Unidade de Hipertensão do Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. O grupo controle foi constituído por 100 amostras de doadores de sangue da Fundação Pró-Sangue/Hemocentro de São Paulo. Em todas as amostras foi realizada a fenotipagem Duffy, a genotipagem DUFFY e a dosagem de IL-8 sérica. A fenotipagem foi realizada pela técnica em tubo. Na genotipagem DUFFY...

‣ Síntese e funcionalização de nanopartículas com oligonucleotídeo para aplicação em genossensores no diagnóstico avançado de predisposição à hipertensão arterial; Synthesis and functionalization of nanoparticles with oligonucleotide for application in genosensors as advanced diagnostic tools for arterial hypertension

Rolim, Thalita Verônica Calheiros
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 09/05/2013 Português
Relevância na Pesquisa
57.200127%
A crescente prevalência de hipertensão arterial na população mundial e os riscos por ela apresentados nas doenças coronarianas eleva a importância de seu controle. Sendo sua causa, frequentemente multifatorial, o tratamento da patologia é dificultado. Fatores ambientais associados à predisposição genética levam o indivíduo a apresentar índices pressóricos elevados de pressão arterial quando comparados a indivíduos que não apresentam tal predisposição. Identificar a predisposição genética seria ideal para amenizar ou, até mesmo, evitar o desenvolvimento da patologia. As nanopartículas estão cada vez mais associadas com biomoléculas, uma vez que suas propriedades associadas às questões médicas podem criar novos métodos potencialmente eficientes, tanto no diagnóstico como na terapêutica. O presente trabalho teve como objetivo a conjugação de nanopartículas de ouro, estabilizadas com dendrímero poli(amidoamina) de geração 4, com oligonucleotídeo para obtenção de genossensores capazes de detectar o polimorfismo de inserção e deleção do gene da enzima conversora de angiotensina I, o qual está intimamente relacionado com a predisposição à hipertensão arterial sistêmica. As nanopartículas foram caracterizadas por Microscopia Eletrônica de Transmissão (TEM)...

‣ Prevalência da hipertensão arterial, avaliada pela medida casual e monitorização residencial da pressão arterial, em comunidades adventistas do sétimo dia no sudoeste paulista; Arterial hypertension prevalence, assessed through casual measurement and home blood pressure monitoring, in Seventh Day Adventist communities in Southeastern São Paulo

Silva, Stael Silvana Bagno Eleuterio da
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 25/09/2012 Português
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Introdução A hipertensão arterial é influenciada por hábitos e estilos de vida e populações específicas como os Adventistas o Sétimo Dia são orientados a incorporar em suas práticas religiosas, hábitos e estilos de vida saudáveis. O objetivo principal desse estudo foi comparar a prevalência da hipertensão arterial em comunidades Adventistas do Sétimo Dia com comunidade não Adventista. Casuística e Métodos O estudo foi realizado na região sudoeste do estado de São Paulo com 547 pessoas (304 Adventistas e 243 não Adventistas). A pressão arterial foi medida com aparelho automático validado e de acordo com as VI Diretrizes Brasileiras de Hipertensão. A religiosidade foi avaliada pela Escala de Duke-DUREL; hábitos alimentares identificados pelo Questionário de Frequência Alimentar; apoio social pela escala de apoio social; consumo de bebida alcoólica pelo Alcohol Use Disorders Identification Test AUDIT e transtornos mentais comuns pelo Self-Reporting Questionnaire (SRQ 20). Foi adotado nível de significância de p<0,05. Resultados A maioria era do sexo feminino, idade de 41,5 anos, etnia branca. A prevalência de hipertensão foi menor nos Adventistas (p<0,05, 25,6% vs 35,4%). Os Adventistas foram diferentes (p<0...

‣ Familial predisposition to hypertension and the association between urinary sodium excretion and blood pressure in a population-based sample of young adults

Moraes, Renan Stoll; Fuchs, Flávio Danni; Costa, Francisco Dalla; Moreira, Leila Beltrami
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
Português
Relevância na Pesquisa
37.59004%
The reasons for the inconsistent association between salt consumption and blood pressure levels observed in within-society surveys are not known. A total of 157 normotensive subjects aged 18 to 35 years, selected at random in a cross-sectional population-based survey, answered a structured questionnaire. They were classified as strongly predisposed to hypertension when two or more first-degree relatives had a diagnosis of hypertension. Anthropometric parameters were obtained and sitting blood pressure was determined with aneroid sphygmomanometers. Sodium and potassium excretion was measured by flame spectrophotometry in an overnight urine sample. A positive correlation between blood pressure and urinary sodium excretion was detected only in the group of individuals strongly predisposed to hypertension, both for systolic blood pressure (r = 0.51, P<0.01) and diastolic blood pressure (r = 0.50, P<0.01). In a covariance analysis, after controlling for age, skin color and body mass index, individuals strongly predisposed to hypertension who excreted amounts of sodium above the median of the entire sample had higher systolic and diastolic blood pressure than subjects classified into the remaining conditions. The influence of familial predisposition to hypertension on the association between salt intake and blood pressure may be an additional explanation for the weak association between urinary sodium excretion and blood pressure observed in within-population studies...

‣ White-coat hypertension and normotension in the League of Hypertension of the Hospital das Clínicas, FMUSP: prevalence, clinical and demographic characteristics

Segre,Carlos A.; Ueno,Rubens K.; Warde,Karim R. J.; Accorsi,Tarso A. D.; Miname,Márcio H.; Chi,Chang K.; Pierin,Angela M. G.; Mion Júnior,Décio
Fonte: Sociedade Brasileira de Cardiologia - SBC Publicador: Sociedade Brasileira de Cardiologia - SBC
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/2003 Português
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OBJECTIVE: To assess the prevalence of white-coat normortension, white-coat hypertension, and white-coat effect. METHODS: We assessed 670 medical records of patients from the League of Hypertension of the Hospital das Clínicas of the Medical School of the University of São Paulo. White-coat hypertension (blood pressure at the medical office: mean of 3 measurements with the oscillometric device ³140 or ³90 mmHg, or both, and ambulatory blood pressure monitoring mean during wakefulness < 135/85) and white-coat normotension (office blood pressure < 140/90 and blood pressure during wakefulness on ambulatory blood pressure monitoring ³ 135/85) were analyzed in 183 patients taking no medication. The white-coat effect (difference between office and ambulatory blood pressure > 20 mmHg for systolic and 10 mmHg for diastolic) was analyzed in 487 patients on treatment, 374 of whom underwent multivariate analysis to identify the variables that better explain the white-coat effect. RESULTS: Prevalence of white-coat normotension was 12%, prevalence of white-coat hypertension was 20%, and prevalence of the white-coat effect was 27%. A significant correlation (p<0.05) was observed between white-coat hypertension and familial history of hypertension...

‣ Familial predisposition to hypertension and the association between urinary sodium excretion and blood pressure in a population-based sample of young adults

Moraes,R.S.; Fuchs,F.D.; Dalla Costa,F.; Moreira,L.B.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/07/2000 Português
Relevância na Pesquisa
37.59004%
The reasons for the inconsistent association between salt consumption and blood pressure levels observed in within-society surveys are not known. A total of 157 normotensive subjects aged 18 to 35 years, selected at random in a cross-sectional population-based survey, answered a structured questionnaire. They were classified as strongly predisposed to hypertension when two or more first-degree relatives had a diagnosis of hypertension. Anthropometric parameters were obtained and sitting blood pressure was determined with aneroid sphygmomanometers. Sodium and potassium excretion was measured by flame spectrophotometry in an overnight urine sample. A positive correlation between blood pressure and urinary sodium excretion was detected only in the group of individuals strongly predisposed to hypertension, both for systolic blood pressure (r = 0.51, P<0.01) and diastolic blood pressure (r = 0.50, P<0.01). In a covariance analysis, after controlling for age, skin color and body mass index, individuals strongly predisposed to hypertension who excreted amounts of sodium above the median of the entire sample had higher systolic and diastolic blood pressure than subjects classified into the remaining conditions. The influence of familial predisposition to hypertension on the association between salt intake and blood pressure may be an additional explanation for the weak association between urinary sodium excretion and blood pressure observed in within-population studies...

‣ The effect of Reiki on blood hypertension

Salles,Léia Fortes; Vannucci,Luciana; Salles,Amanda; Silva,Maria Júlia Paes da
Fonte: Escola Paulista de Enfermagem, Universidade Federal de São Paulo Publicador: Escola Paulista de Enfermagem, Universidade Federal de São Paulo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2014 Português
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Objective Determining the immediate effect of Reiki on abnormal blood pressure. Methods An experimental, double-blind study, in which were included 66 hypertensive patients, randomized to the three following study groups: control, placebo and experimental. The intervention lasted 20 minutes, the control group remained at rest, the placebo group received an imitation of the studied technique (mock Reiki) and the experimental group received the Reiki technique. Blood pressure was measured before and after the intervention by the same person with the same instrument. Results There was a decrease in blood pressure in the three groups and the reduction was greater in the experimental group, followed by the placebo and the control group. The ANOVA model for repeated measures showed a statistically significant difference among the groups (p <0.0001). Conclusion Reiki had a positive effect on reducing abnormal blood pressure, suggesting to be a complementary technique for the control of hypertension.

‣ Chronic maternal hypertension characterized by renal dysfunction is associated with reduced placental blood flow during late gestation in rabbits

McArdle, A.; Roberts, C.; Maduwegedera, D.; Flower, R.; Denton, K.
Fonte: Amer Physiological Soc Publicador: Amer Physiological Soc
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
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37.633218%
Maternal hypertension associated with renal disease is a common pregnancy complication. Previously, we have shown in a rabbit model of mild hypertension that offspring from hypertensive mothers have increased blood pressure as adults. In human pregnancy, hypertension has been associated with decreased utero-placental blood flow. The aim of this study was to determine placental blood flow (PBF) in mild (2-kidney-1-wrapped; 2K-1W) and moderate (2-kidney-2-wrapped; 2K-2W) rabbit models of maternal hypertension. We hypothesized that PBF would be inversely related to the severity of the hypertension. PBF and renal blood flow (RBF) were measured using microspheres on day 28 of a 32-day gestation, in normotensive (sham), 2K-1W, and 2K-2W hypertensive groups. Mean arterial pressure (MAP, approximately 7 mmHg, P < 0.05) was increased, and RBF ( approximately 35%, P < 0.05) was reduced in the 2K-1W and 2K-2W (MAP approximately 20 mmHg, P < 0.01; RBF approximately 53%, P < 0.05) groups compared with the sham group. In the 2K-1W group, PBF fell by approximately 12% (P = 0.08) and fetal-to-placental weight ratio increased by approximately 12% (P < 0.01) compared with the sham group, reflecting an increase in the functional capacity of the placenta to deliver nutrients to the fetus. In the 2K-2W group...

‣ Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study

Head, G.A.; Mihailidou, A.S.; Duggan, K.A.; Beilin, L.J.; Berry, N.; Brown, M.A.; Bune, A.J.; Cowley, D.; Chalmers, J.P.; Howe, P.R.C.; Hodgson, J.; Ludbrook, J.; Mangoni, A.A.; McGrath, B.P.; Nelson, M.R.; Sharman, J.E.; Stowasser, M.
Fonte: BMJ Publishing Group Publicador: BMJ Publishing Group
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
Relevância na Pesquisa
37.57663%
BACKGROUND: Twenty-four hour ambulatory blood pressure thresholds have been defined for the diagnosis of mild hypertension but not for its treatment or for other blood pressure thresholds used in the diagnosis of moderate to severe hypertension. We aimed to derive age and sex related ambulatory blood pressure equivalents to clinic blood pressure thresholds for diagnosis and treatment of hypertension. METHODS: We collated 24 hour ambulatory blood pressure data, recorded with validated devices, from 11 centres across six Australian states (n=8575). We used least product regression to assess the relation between these measurements and clinic blood pressure measured by trained staff and in a smaller cohort by doctors (n=1693). RESULTS: Mean age of participants was 56 years (SD 15) with mean body mass index 28.9 (5.5) and mean clinic systolic/diastolic blood pressure 142/82 mm Hg (19/12); 4626 (54%) were women. Average clinic measurements by trained staff were 6/3 mm Hg higher than daytime ambulatory blood pressure and 10/5 mm Hg higher than 24 hour blood pressure, but 9/7 mm Hg lower than clinic values measured by doctors. Daytime ambulatory equivalents derived from trained staff clinic measurements were 4/3 mm Hg less than the 140/90 mm Hg clinic threshold (lower limit of grade 1 hypertension)...

‣ Self-reported knowledge and awareness about blood pressure and hypertension: a cross-sectional study of a random sample of men and women aged 60-74 years

Qvist, I.; Thomsen, M.D.; Lindholt, J.S.; Ibsen, H.; Hendriks, J.M.L.; Frost, L.
Fonte: Dove Medical Press Publicador: Dove Medical Press
Tipo: Artigo de Revista Científica
Publicado em //2014 Português
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BACKGROUND: In general, it is assumed that patient education, by increasing knowledge, may change behavior and lifestyle and promote health. In this context, it is a surprise that knowledge and awareness about blood pressure and hypertension among elderly people is poor. We hypothesized that knowledge about blood pressure and hypertension would be better among individuals with self-reported hypertension compared with subjects without self-reported hypertension. METHODS: We mailed a questionnaire to a random sample of 1,000 subjects living in the municipality of Silkeborg, Denmark. The study sample was drawn from the Central Person Registry. RESULTS: The response rate was 72%. Of these, 43% of responders had self-reported hypertension. The people with self-reported hypertension were older, less educated, had higher self-reported blood cholesterol levels, had higher body weight, and more often had a family history of hypertension. More than 80% reported that overweight and obesity increases blood pressure. More than 60% reported that untreated hypertension may cause heart disease or stroke. More than half of the responders did not know their blood pressure, and only 21% knew that hypertension can occur without symptoms. Knowledge about hypertension was independent of self-reported hypertension status...

‣ Prevalência de obesidade e hipertensão arterial e associação com fatores de risco em escolares da cidade de Sorocaba, São Paulo, Brasil; Obesity and arterial hypertension prevalence and their association with risk factors in schoolchildren from Sorocaba city, São Paulo, Brazil

Isabela Annunziato Ramos Mazaro
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 02/06/2011 Português
Relevância na Pesquisa
37.641921%
INTRODUÇÃO: Nas últimas décadas houve aumento significativo da prevalência da obesidade e de suas complicações na faixa etária pediátrica, incluindo a hipertensão arterial. OBJETIVO: Estimar a prevalência da obesidade e da hipertensão arterial e da associação destas com fatores de risco em estudantes de Sorocaba (SP). MÉTODO: Estudo transversal, de base populacional fixa e amostra aleatória com observação individual de 680 alunos de 7 a 11 anos. Foram avaliados: sexo, idade, região de moradia, classificação econômica, antecedentes pessoais, maternos e paternos para hipertensão arterial, doença renal e cardíaca, realização de atividade física fora da escola, tempo com TV/VG/PC. Foram realizadas medidas de: peso, altura, circunferência da cintura, dobras cutâneas, PA e verificado a presença de acanthosis nigricans. Calculou-se a prevalência de sobrepeso, obesidade e excesso de peso; pré-hipertensão, hipertensão arterial e de PA elevada. Para associação destes com as demais variáveis empregou-se o teste do qui-quadrado ou o Exato de Fisher (p<0,05). Determinou-se a razão de chances prevalente bruta e ajustada por regressão logística. RESULTADOS: Do total: 49% eram do sexo masculino, sendo, 19% com 7 anos; 23...

‣ High blood pressure six weeks postpartum after hypertensive pregnancy disorders at term is associated with chronic hypertension

Visser, V.; Hermes, W.; Franx, A.; Koopmans, C.; van Pampus, M.; Mol, B.; de Groot, C.
Fonte: Elsevier BV Publicador: Elsevier BV
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
Relevância na Pesquisa
37.660085%
OBJECTIVES: Hypertension in pregnancy is associated with cardiovascular disease (CVD) later in life. Blood pressure monitoring in women who experienced hypertension in pregnancy after puerperium has been suggested to be important for early detection and prevention of CVD. The aim of this study is to evaluate if hypertension six weeks postpartum is associated with chronic hypertension in women with a history of term hypertensive pregnancy disorders. STUDY DESIGN: Women with a history of term gestational hypertension or preeclampsia were included in a follow up study of the HYPITAT trial. Blood pressures were measured six weeks and 2.5years postpartum according to the study protocol. MAIN OUTCOME MEASURES: Hypertension was defined as a diastolic blood pressure ⩾90mmHg and/or a systolic blood pressure ⩾140mmHg or use of antihypertensive medication. Differences in categorical variables between groups were analyzed by Chi-Square tests. Blood pressure was analyzed using unpaired t-tests and Wilcox ranked tests. RESULTS: Among 187 women who had term hypertensive pregnancy disorders, 75 (40%) had hypertension at six weeks postpartum. Of these 46 (61%) had hypertension 2.5years postpartum. In contrast, of 112 women without hypertension at six weeks postpartum...

‣ Self-Screening and Non-Physician Screening for Hypertension in Communities: A Systematic Review

Fleming, Susannah; Atherton, Helen; McCartney, David; Hodgkinson, James; Greenfield, Sheila; Hobbs, Frederick David Richard; Mant, Jonathan; McManus, Richard J.; Thompson, Matthew; Ward, Alison; Heneghan, Carl
Fonte: Oxford Journals on behalf of American Journal of Hypertension, Ltd. Publicador: Oxford Journals on behalf of American Journal of Hypertension, Ltd.
Tipo: Article; published version
Português
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47.239497%
This is the final version of the article. It was first available from Oxford University Press via http://dx.doi.org/10.1093/ajh/hpv029; Background Community-based self-screening may provide opportunities to increase detection of hypertension, and identify raised blood pressure (BP) in populations who do not access healthcare. This systematic review aimed to evaluate the effectiveness of non-physician screening and self-screening of BP in community settings. METHODS We searched the Cochrane Central Trials Register, Medline, Embase, CINAHL, and Science Citation Index & Conference Proceedings Citation Index?Science to November 2013 to identify studies reporting community- based self-screening or non-physician screening for hypertension in adults. Results were stratified by study site, screener, and the cut-off used to define high screening BP. RESULTS We included 73 studies, which described screening in 9 settings, with pharmacies (22%) and public areas/retail (15%) most commonly described. We found high levels of heterogeneity in all analyses, despite stratification. The highest proportions of eligible participants screened were achieved by mobile units (range 21%?88%) and pharmacies (range 40%?90%). Self-screeners had similar median rates of high BP detection (25%?35%) to participants in studies using other screeners. Few (16%) studies reported referral to primary care after screening. However...

‣ Hipertensão arterial sistêmica e depressão; Hypertension and depression

Scalco, Andréia Zavaloni; Scalco, Mônica Zavaloni; Azul, João Batista Serro; Lotufo Neto, Francisco
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 01/06/2005 Português
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37.602515%
Apesar das altas prevalências de hipertensão arterial sistêmica e de depressão, o estudo da relação entre depressão e pressão arterial tem recebido pouca atenção da literatura. Nesse artigo são revisados os aspectos epidemiológicos, patofisiológicos, prognósticos e implicações no tratamento, relacionados à associação entre depressão e hipertensão arterial sistêmica. O método utilizado foi consulta ao banco de dados bibliográficos Medline, utilizando-se as palavras chave depression, blood pressure, blood pressure variability, physical morbidity, hypertension, mood, stress, hypertension, antidepressive agents e genetics, no período de 1980 a 2004. Encontramos descrições de prevalência aumentada de hipertensão em pacientes deprimidos, prevalência aumentada de depressão em pacientes hipertensos, associação entre sintomatologia depressiva e hipotensão e alteração da variação circadiana da pressão arterial de pacientes deprimidos. Acredita-se que mecanismos envolvendo hiperatividade de sistema nervoso simpático e influências genéticas possam ser a base fisiopatológica da relação entre depressão e hipertensão arterial sistêmica. Além disso, a presença de depressão pode piorar o curso da doença hipertensiva...

‣ Lipopolysaccharide Reverses Adrenocorticotrophic Hormone-Induced Hypertension in the Rat

Zhang, Yi; Schyvens, Chris; McKenzie, Katja; Morris, Brian; Whitworth, Judith
Fonte: Japanese Society for Hypertension Publicador: Japanese Society for Hypertension
Tipo: Artigo de Revista Científica
Português
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47.31173%
Lipopolysaccharide (LPS) was used to stimulate nitric oxide (NO) release and investigate the effect of endogenous NO on adrenocorticotrophic hormone (ACTH)-induced hypertension in rats. After preliminary studies to determine the appropriate dose of LPS, 40 male Sprague-Dawley rats were treated with ACTH (200 μg/kg/day, s.c.) or saline (sham) for 8 days and then given a single dose of LPS (10 mg/kg, i.p.) or saline. ACTH treatment was continued for a further 5 days. Systolic blood pressure (SBP) was measured daily using the tail cuff method. Results were expressed as the mean±SEM. ACTH treatment significantly increased SBP (from 105±3 to 129±4 mmHg; p<0.05), whereas saline had no effect on SBP. The ACTH-induced increase in SBP was reversed by LPS injection (from 125±6 to 102±7 mmHg; p<0.05). SBP was also decreased in sham + LPS-treated rats compared with that of sham + saline-treated rats (p<0.05), but the SBP change in response to LPS was greater in ACTH-treated than in sham-treated rats (-23 vs. -8 mmHg; p<0.05). These data are compatible with the notion that reduced NO availability plays a role in ACTH-induced hypertension.

‣ Ocupação e hipertensão; Work and high blood pressure

Cordeiro, Ricardo; Fischer, Frida M.; Lima Filho, Euclydes C.; Moreira Filho, Djalma C.
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; ; Formato: application/pdf
Publicado em 01/10/1993 Português
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Com base em revisão bibliográfica discute-se a literatura produzida nas décadas de 70 e 80, no campo da epidemiologia da hipertensão arterial sistêmica entre trabalhadores. Analisa-se não apenas o ponto de vista do conhecimento gerado, mas também os aspectos relacionados ao instrumental teórico-metodológico empregado.; Scientific reports on Arterial Blood Hypertension for the period from 1970 to 1989 are reviewed, with special reference to its epidemiological focusing among workers. The knowledge gained and the theoretical and methodological advances associated with it are assessed.

‣ Incidencia de la hipertensión arterial en gestantes con oligohidramnios

Fonte: Revista Cubana de Obstetricia y Ginecología Publicador: Revista Cubana de Obstetricia y Ginecología
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2005 Português
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A retrospective longitudinal and descriptive study was undertaken to find out the incidence of both chronic and gestational blood hypertension on gestation of 28 weeks and over complicated with oligohydrammnios, and compare it with that of idiopathic oligohidramnios, at the gynecological and obstetric hospital of Guanabacoa municipality during 2 years (2002 and 2003). One hundred sixty four patients (sample) with oligohydramnios out of 200 cases diagnosed in this period (universe) were divided into two groups to be studied: one included 60 cases with high blood pressure and the other comprised 104 cases of idiopathic cause. Other types of causes were not included. The results showed that the main cause of oligohydramnios was idiopathic but HBP holds a significant position; the majority were considered as slight (ILA from4 to 5 cm) and they occur in term pregnancies in both groups, although in hypertensives, they increase preterm whereas in idiopathic cases, they occur mostly postterm. The number of cesarean sections performed as well as perinatal morbidity and mortality were slightly higher in hypertensive patients. It was concluded that high blood pressure plays an important role in the origin of oligohydramnios particularly in term pregnancies...

‣ Blood pressure control, hypertension, awareness, and treatment in adults with diabetes in the United States-Mexico border region

Vijayaraghavan,Maya; He,Guozhong; Stoddard,Pamela; Schillinger,Dean
Fonte: Organización Panamericana de la Salud Publicador: Organización Panamericana de la Salud
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2010 Português
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OBJETIVE: To determine prevalence of blood pressure control, hypertension, hypertension awareness, and antihypertensive treatment among adults (> 18 years old) with diabetes living in the border region between the United States of America and Mexico, and to explore variation in those variables between all adults on the Mexican side of the border ("Mexicans") and three groups on the U.S. side of the border ("all U.S. adults," "U.S.-born Hispanics," and "Mexican immigrants"). METHODS: Using data from Phase I (February 2001-October 2002) of the U.S.-Mexico Border Diabetes Prevention and Control Project, a prevalence study of type 2 diabetes and its risk factors, age-adjusted prevalence of hypertension-related variables was calculated for the sample (n = 682) and differences between the border groups were examined through logistic regression. RESULTS: Less than one-third of the sample had controlled blood pressure (< 130/80 mm Hg), almost half had hypertension (>140/90 mm Hg), and hypertension awareness and treatment were inadequate. After adjusting for demographics, body mass index, and access to health care, there were no differences in blood pressure control, hypertension, hypertension awareness, or treatment between Mexicans and both U.S. adults and Mexican immigrants. However...