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‣ Estudo de uma nova técnica atraumática para o diagnóstico de Demodex canis e sua comparação com técnicas já utilizadas

Lousada, Rita Maria Sousa
Fonte: Universidade de Lisboa. Faculdade de Medicina Veterinária Publicador: Universidade de Lisboa. Faculdade de Medicina Veterinária
Tipo: Dissertação de Mestrado
Publicado em 27/01/2015 Português
Relevância na Pesquisa
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Dissertação de Mestrado Integrado em Medicina Veterinária; A demodicose canina (DC) é uma doença cutânea inflamatória parasitária, causada pela proliferação excessiva dos ácaros foliculares comensais do género Demodex. A demodicose localizada (DL) é uma forma benigna auto-limitante que não requer tratamento acaricida. Por outro lado, a demodicose generalizada (DG) pode ser grave e colocar a vida do paciente em risco. Geralmente a DC não é difícil de diagnosticar através dos métodos mais comuns (raspagens cutâneas profundas e/ou tricograma), no entanto, ainda são vários os casos que chegam às consultas de referência de dermatologia, quer por baixo índice de suspeita da doença, não se chegando a realizar a sua pesquisa, ou por falhas na realização dos métodos de diagnóstico. As raspagens profundas são o método de diagnóstico de eleição, embora este seja considerado traumatizante. O tricograma não apresenta esta desvantagem, porém, a sua sensibilidade é considerada mais baixa, variando desde 40 a 85% consoante os autores. Deste modo, seria útil encontrar um método de diagnóstico atraumático que mantivesse uma sensibilidade elevada. A sensibilidade do método da fita adesiva foi recentemente estudada...

‣ Is Demodex really non-pathogenic?

PENA,Gil Patrus; ANDRADE FILHO,José de Souza
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2000 Português
Relevância na Pesquisa
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Although usually considered a non-pathogenic parasite in parasitological textbooks, Demodex folliculorum has been implicated as a causative agent for some dermatological conditions, such as rosacea-like eruptions and some types of blepharitis. Several anecdotal reports have demonstrated unequivocal tissue damage directly related to the presence of the parasite. However, this seems to be exceedingly rare, in contrast with the marked prevalence of this infestation. We have had the opportunity to observe one of such cases. A 38-year-old woman presented with rosacea-like papular lesions in her right cheek. Histopathological examination revealed granulomatous dermal inflammation with a well-preserved mite phagocytized by a multinucleated giant cell. This finding may be taken as an evidence for the pathogenicity of the parasite, inasmuch as it does not explain how such a common parasite is able to produce such a rare disease.

‣ Prevalencia de Demodex folliculorum e Demodex brevis em uma amostra da população de Botucatu, São Paulo, Brasil

Madeira,N.G.; Sogayar,M.I.L.
Fonte: Sociedade Brasileira de Medicina Tropical - SBMT Publicador: Sociedade Brasileira de Medicina Tropical - SBMT
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/1993 Português
Relevância na Pesquisa
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Pela primeira vez no Brasil foi realizado um levantamento para se conhecer a distribuição do D. folliculorum e D. brevis no homem. Uma amostra de 100 pessoas atendida em clínica estética foi examinada, procurando-se estudar a associação entre a presença de ácaros e fatores como idade, raça e sexo do hospedeiro. O material colhido da região facial dos indivíduos foi montado em lâminas com o meio de Berlese. Das 100 pessoas examinadas, 72 % foram positivas. Dos casos positivos, 51 % estavam infestados pelo D. folliculorum, 2% pelo D. brevis e 19% apresentaram-se parasitados por ambas as espécies.

‣ Under the lash: Demodex mites in human diseases

Lacey, Noreen; Kavanagh, Kevin; Tseng, Scheffer C.G.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 01/08/2009 Português
Relevância na Pesquisa
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Demodex mites, class Arachnida and subclass Acarina, are elongated mites with clear cephalothorax and abdomens, the former with four pairs of legs. There are more than 100 species of Demodex mite, many of which are obligatory commensals of the pilosebaceous unit of mammals including cats, dogs, sheep, cattle, pigs, goats, deer, bats, hamsters, rats and mice. Among them, Demodex canis, which is found ubiquitously in dogs, is the most documented and investigated. In excessive numbers D. canis causes the inflammatory disease termed demodicosis (demodectic mange, follicular mange or red mange), which is more common in purebred dogs and has a hereditary predisposition in breeding kennels1. Two distinct Demodex species have been confirmed as the most common ectoparasite in man. The larger Demodex folliculorum, about 0.3–0.4 mm long, is primarily found as a cluster in the hair follicle (Figure 1a), while the smaller Demodex brevis, about 0.2–0.3 mm long with a spindle shape and stubby legs, resides solitarily in the sebaceous gland (Figure 1b). These two species are also ubiquitously found in all human races without gender preference. The pathogenic role of Demodex mites in veterinary medicine is not as greatly disputed as in human diseases. In this article...

‣ Sociodemographic characteristics and risk factor analysis of Demodex infestation (Acari: Demodicidae)*

Zhao, Ya-e; Guo, Na; Xun, Meng; Xu, Ji-ru; Wang, Mei; Wang, Duo-lao
Fonte: Zhejiang University Press Publicador: Zhejiang University Press
Tipo: Artigo de Revista Científica
Publicado em /12/2011 Português
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To identify sociodemographic characteristics and risk factor of Demodex infestation, 756 students aged 13–22 years in Xi’an, China were sampled for the school-based cross-sectional study. Demodex was examined using the cellophane tape method (CTP). The results showed that the total detection rate of Demodex was 67.6%. Logistic regression analysis revealed that five variables (gender, residence, sharing sanitary ware, frequency of face-wash per day, and use of facial cleanser) were found to be uncorrelated with Demodex infestation, whereas three variables (age, skin type, and skin disease) were found to be independent correlates. Students aged over 18 years had 22.1 times higher odds of Demodex infestation compared to those under 16 years and students aged 16–18 years also had 2.1 times higher odds compared to those aged 13–15 years. Odds of having a Demodex infestation for oily or mixed skin were 2.1 times those for dry or neutral skin. Students with a facial skin disease had 3.0 times higher odds of being infested with Demodex compared to those without. The inception rate of students with facial dermatoses increased in parallel with increasing mite count. The inception rates were 21.3%, 40.7%, 59.2%, and 67.7% in the negative...

‣ Facial dermatosis associated with Demodex: a case-control study*

Zhao, Ya-e; Peng, Yan; Wang, Xiang-lan; Wu, Li-ping; Wang, Mei; Yan, Hu-ling; Xiao, Sheng-xiang
Fonte: Zhejiang University Press Publicador: Zhejiang University Press
Tipo: Artigo de Revista Científica
Publicado em /12/2011 Português
Relevância na Pesquisa
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Demodex has been considered to be related with multiple skin disorders, but controversy persists. In this case-control study, a survey was conducted with 860 dermatosis patients aged 12 to 84 years in Xi’an, China to identify the association between facial dermatosis and Demodex. Amongst the patients, 539 suffered from facial dermatosis and 321 suffered from non-facial dermatosis. Demodex mites were sampled and examined using the skin pressurization method. Multivariate regression analysis was applied to analyze the association between facial dermatosis and Demodex infestation, and to identify the risk factors of Demodex infestation. The results showed that total detection rate of Demodex was 43.0%. Patients aged above 30 years had higher odds of Demodex infestation than those under 30 years. Compared to patients with neutral skin, patients with mixed, oily, or dry skin were more likely to be infested with Demodex (odds ratios (ORs) were 2.5, 2.4, and 1.6, respectively). Moreover, Demodex infestation was found to be statistically associated with rosacea (OR=8.1), steroid-induced dermatitis (OR=2.7), seborrheic dermatitis (OR=2.2), and primary irritation dermatitis (OR=2.1). In particular, ORs calculated from the severe infestation (≥5 mites/cm2) rate were significantly higher than those of the total rate. Therefore...

‣ A meta-analysis of association between acne ulgaris and Demodex infestation*

Zhao, Ya-e; Hu, Li; Wu, Li-ping; Ma, Jun-xian
Fonte: Zhejiang University Press Publicador: Zhejiang University Press
Tipo: Artigo de Revista Científica
Publicado em /03/2012 Português
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Until now, etiology of acne vulgaris is still uncertain. Although clinicians usually deny the association between Demodex infestation and acne vulgaris, it has been proved in some clinical practices. To confirm the association between Demodex infestation and acne vulgaris, a meta-analysis was conducted. Predefined selection criteria were applied to search all published papers that analyzed the association between Demodex infestation and acne vulgaris (January 1950 to August 2011) in ISI Web of Knowledge, MEDLINE, and China National Knowledge Infrastructure (CNKI) databases. A meta-analysis was performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) based on fixed effects models or random effects models. We enrolled the 60 Chinese and 3 English papers in this meta-analysis, which covered Turkey and 25 different provinces/municipalities in China and 42 130 participants including students and residents, aged from 1 to 78 years. The pooled OR in random effects models is 2.80 (95% CI, 2.34–3.36). Stability is robust according to sensitivity analysis. The fail-safe number is 18 477, suggesting that at least 18 477 articles with negative conclusions would be needed to reverse the conclusion that acne vulgaris was related to Demodex infestation. So the effect of publication bias was insignificant and could be ignored. It was concluded that acne vulgaris is associated with Demodex infestation. This indicates that when regular treatments for acne vulgaris are ineffective...

‣ Cloning and sequence analysis of chitin synthase gene fragments of Demodex mites*

Zhao, Ya-e; Wang, Zheng-hang; Xu, Yang; Xu, Ji-ru; Liu, Wen-yan; Wei, Meng; Wang, Chu-ying
Fonte: Zhejiang University Press Publicador: Zhejiang University Press
Tipo: Artigo de Revista Científica
Publicado em /10/2012 Português
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To our knowledge, few reports on Demodex studied at the molecular level are available at present. In this study our group, for the first time, cloned, sequenced and analyzed the chitin synthase (CHS) gene fragments of Demodex folliculorum, Demodex brevis, and Demodex canis (three isolates from each species) from Xi’an China, by designing specific primers based on the only partial sequence of the CHS gene of D. canis from Japan, retrieved from GenBank. Results show that amplification was successful only in three D. canis isolates and one D. brevis isolate out of the nine Demodex isolates. The obtained fragments were sequenced to be 339 bp for D. canis and 338 bp for D. brevis. The CHS gene sequence similarities between the three Xi’an D. canis isolates and one Japanese D. canis isolate ranged from 99.7% to 100.0%, and those between four D. canis isolates and one D. brevis isolate were 99.1%–99.4%. Phylogenetic trees based on maximum parsimony (MP) and maximum likelihood (ML) methods shared the same clusters, according with the traditional classification. Two open reading frames (ORFs) were identified in each CHS gene sequenced, and their corresponding amino acid sequences were located at the catalytic domain. The relatively conserved sequences could be deduced to be a CHS class A gene...

‣ Ocular Surface Discomfort and Demodex: Effect of Tea Tree Oil Eyelid Scrub in Demodex Blepharitis

Koo, Hyun; Kim, Tae Hyung; Kim, Kyoung Woo; Wee, Sung Wook; Chun, Yeoun Sook; Kim, Jae Chan
Fonte: The Korean Academy of Medical Sciences Publicador: The Korean Academy of Medical Sciences
Tipo: Artigo de Revista Científica
Português
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The purpose of this study was to evaluate the relation between ocular discomfort and ocular Demodex infestation, and therapeutic effects of tea tree oil (TTO) in Demodex blepharitis patients. Three hundred and thirty-five patients with ocular discomfort were evaluated for ocular Demodex infestation and subjective symptoms with ocular surface discomfort index (OSDI) score. Among them, Demodex-infested patients were randomized to receive either eyelid scrubbing with TTO (TTO group,106 patients) or without TTO (Control group, 54 patients) for 1 month. Demodex were found in 84% of patients with ocular discomfort. The number of Demodex was significantly correlated with age (P = 0.04) and OSDI score (P = 0.024). After eyelid scrub treatment, Demodex count was reduced from 4.0 ± 2.5 to 3.2 ± 2.3 in the TTO group (P = 0.004) and from 4.3 ± 2.7 to 4.2 ± 2.5 in the control group (P = 0.27). Also, OSDI score was reduced from 34.5 ± 10.7 to 24.1 ± 11.9 in the TTO group (P = 0.001) and from 35.3 ± 11.6 to 27.5 ± 12.8 in the control group (P = 0.04). In conclusion, Demodex number showed a significant positive correlation with age and subjective ocular discomfort. The tea tree oil eyelid scrub treatment is effective for eliminating ocular Demodex and improving subjective ocular symptoms.

‣ Demodex spp. Infestation in a breast-cancer patient: A case report

Olt, Serdar; Yalçın, Gülter Gülter; Uysal, Özlem Sönmez; Karakeçe, Engin; Çiftci, Ihsan Hakkı
Fonte: Medknow Publications & Media Pvt Ltd Publicador: Medknow Publications & Media Pvt Ltd
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
Relevância na Pesquisa
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Demodex folliculorum and Demodex brevis are obligatory parasites that live in sebaceous glands and follicles. When immune system becomes suppressed by any reason, patients become vulnerable to obligatory parasites like D. folliculorum and D. brevis. Immune system becomes suppressed in cancer patients who undergo chemotherapy, and as a result these patients become vulnerable to infestations. In our case, a 45 year-old female has been admitted to oncology clinic for a medical treatment of breast cancer. Her systematic physical examination was normal, except redness on her cheeks and forehead. There was no abnormality in biochemical and haematological laboratory values. We have decided to apply chemotherapy of Adriamycin, cyclophosphamide and 5-fluorouracil. Due to the itchy redness on her cheeks and forehead, we had performed an examination for demodex before chemotherapy; and we have identified 20 mites/cm2 on her right and left cheeks, and 15 mites/cm2 on her forehead. When our patient had came our clinic with increasing complaint of itchy rash, after the first course of chemotherapy we have reexamined demodex. The result of microscopic examination revealed large amount of demodex of 50 mites/cm2 on her right and left cheeks and 30 mites/cm2 on her forehead...

‣ Human Demodex Mite: The Versatile Mite of Dermatological Importance

Rather, Parvaiz Anwar; Hassan, Iffat
Fonte: Medknow Publications & Media Pvt Ltd Publicador: Medknow Publications & Media Pvt Ltd
Tipo: Artigo de Revista Científica
Publicado em //2014 Português
Relevância na Pesquisa
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Demodex mite is an obligate human ecto-parasite found in or near the pilo-sebaceous units. Demodex folliculorum and Demodex brevis are two species typically found on humans. Demodex infestation usually remains asymptomatic and may have a pathogenic role only when present in high densities and also because of immune imbalance. All cutaneous diseases caused by Demodex mites are clubbed under the term demodicosis or demodicidosis, which can be an etiological factor of or resemble a variety of dermatoses. Therefore, a high index of clinical suspicion about the etiological role of Demodex in various dermatoses can help in early diagnosis and appropriate, timely, and cost effective management.

‣ A Study on the Nature of Association between Demodex Mites and Bacteria Involved in Skin and Meibomian Gland Lesions of Demodectic Mange in Cattle

Abu-Samra, Mukhtar Taha; Shuaib, Yassir Adam
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
Português
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The nature of association between Demodex mites and bacteria involved in bovine demodectic mange lesions and the normal flora inhabiting the skin of noninfected animals was investigated. Demodex bovis and D. ghanensis mites were isolated from the infected purulent material extracted from skin and meibomian gland lesions, respectively. The mites could not be demonstrated in skin brushings or impression smears from the eyes of noninfected cattle. Pathogenic bacteria (Staphylococcus aureus and Streptococcus pyogenes (Group A)) and opportunistic organisms (Proteus vulgaris, Pseudomonas aeruginosa, Staphylococcus epidermidis, and Trueperella pyogenes) were isolated from skin lesions of demodectic mange, and Moraxella bovis and Staphylococcus aureus were isolated from meibomian gland lesions. Bacillus subtilis, Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pyogenes (Group A) were isolated from skin brushings from noninfected cattle. The nature of association between Demodex mites and bacteria in demodectic mange lesions is synergistic and of equal significance. Pathogenic and opportunistic bacteria facilitated the establishment of Demodex mites in the lesions produced and provided an excellent microclimate for the mites to propagate and reproduce...

‣ Ubiquity and Diversity of Human-Associated Demodex Mites

Thoemmes, Megan S.; Fergus, Daniel J.; Urban, Julie; Trautwein, Michelle; Dunn, Robert R.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 27/08/2014 Português
Relevância na Pesquisa
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Demodex mites are a group of hair follicle and sebaceous gland-dwelling species. The species of these mites found on humans are arguably the animals with which we have the most intimate interactions. Yet, their prevalence and diversity have been poorly explored. Here we use a new molecular method to assess the occurrence of Demodex mites on humans. In addition, we use the 18S rRNA gene (18S rDNA) to assess the genetic diversity and evolutionary history of Demodex lineages. Within our samples, 100% of people over 18 years of age appear to host at least one Demodex species, suggesting that Demodex mites may be universal associates of adult humans. A phylogenetic analysis of 18S rDNA reveals intraspecific structure within one of the two named human-associated Demodex species, D. brevis. The D. brevis clade is geographically structured, suggesting that new lineages are likely to be discovered as humans from additional geographic regions are sampled.

‣ Volatile oils of Chinese crude medicines exhibit antiparasitic activity against human Demodex with no adverse effects in vivo

LIU, JI-XIN; SUN, YAN-HONG; LI, CHAO-PIN
Fonte: D.A. Spandidos Publicador: D.A. Spandidos
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
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Demodex is a type of permanent obligatory parasite, which can be found on the human body surface. Currently, drugs targeting Demodex usually result in adverse effects and have a poor therapeutic effect. Thus, the aim of the present study was to investigate the use of Chinese crude medicine volatile oils for targeting and inhibiting Demodex in vitro. The volatile oils of six Chinese crude medicines were investigated, including clove, orange fruit, Manchurian wildginger, cinnamon bark, Rhizome Alpiniae Officinarum and pricklyash peel, which were extracted using a distillation method. The exercise status of Demodex folliculorum and Demodex brevis and the antiparasitic effects of the volatile oils against the two species were observed using microscopy. A skin irritation test was used to examine the irritation intensity of the volatile oils. In addition, an acute toxicity test was utilized to observe the toxicity effects of the volatile oils on the skin. Xin Fumanling ointment was employed as a positive control to identify the therapeutic effects of the volatile oils. The results indicated that all six volatile oils were able to kill Demodex efficiently. In particular, the clove volatile oil was effective in inducing optimized anti-Demodex activity. The lethal times of the volatile oils were significantly decreased compared with the Xin Fumanling ointment (P<0.05). Furthermore...

‣ Demodex sp. as a Potential Cause of the Abandonment of Soft Contact Lenses by Their Existing Users

Tarkowski, Witold; Moneta-Wielgoś, Joanna; Młocicki, Daniel
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
Português
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Demodex mites may be a potential etiological factor in the development of various eye and skin disorders. The aim of the study was to investigate the presence of Demodex in the hair follicles of eyelashes and their potential influence on abandoning soft contact lenses which had been previously well tolerated by their users. A group of 62 users of contact lenses (28 with emerging discomfort and 34 without discomfort) were examined. There is a need to check the existence of a relationship between D. folliculorum or/and D. brevis infestation and the emergence of intolerance to the presence of soft contact lenses. The removed lashes were examined under light microscopy, applying standard parasitological methods if demodicosis is suspected. A positive result was assumed if at least one adult stage, larva, protonymph/nymph, or egg of D. folliculorum and/or D. brevis was present. A positive correlation was observed between the presence of Demodex and intolerance to contact lenses by their existing users (p < 0.05), and Demodex sp. infections were observed in 92.86% of patients with intolerance to contact lenses. Our results provide further evidence for the pathogenic role played by the mites in the development of eye diseases.

‣ Acompanhamento cl??nico, histopatol??gico e avalia????o dos n??veis de interleucina 10 de c??es com demodicose cr??nica

Felix, Anelize de Oliveira Campello
Fonte: Universidade Federal de Pelotas; Veterin??ria; Programa de P??s-Gradua????o em Veterin??ria; UFPel; BR Publicador: Universidade Federal de Pelotas; Veterin??ria; Programa de P??s-Gradua????o em Veterin??ria; UFPel; BR
Tipo: Dissertação Formato: application/pdf
Português
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Demodicosis is considered one of the most severe canine skin disease. It is caused by the excessive proliferation of the Demodex canis mite, normal member of the canine skin. Skin lesions caused by the parasite predispose the skin to secondary infections that will further aggravate the patients clinical aspects. The objective of this work was to evaluate the clinical a histopathological evolution of the disease, as well as to study the seric levels of interleukin 10 (IL10) in demodicosis patients. The first study was conducted using 20 animals, 10 demodicosis patients (GD), and 10 control dogs (GC). All these animals were clinically evaluated, and submitted to deep skin scraping in search of Demodex mites. The dogs in the GD group were treated with moxidectin and evaluated in days 0, 20, 40, 60, and 80. Five of these animals were healed and submitted to skin biopsies on days 0 and 80, for the observation of histopathological alterations. A second study used 26 animals, 17 on G1 (demodicosis patients) and 9 on G2 (healthy dogs). All G1 animals were positive for demodicosis on the skin scrape test, and were submitted to clinical evaluation. Blood was harvested from all the animals, with the interleukin 10 dosage being carried out with the comrcial kit Quantikine Canine IL-10 Immunoassay?? (R&D Systems) . Results obtained in the first experiment showed considerable clinical and scrape test improvement in GD...

‣ Demodecose canina: aspectos da sua abordagem terapêutica

Mota, Tiago Evaristo Borges
Fonte: Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária Publicador: Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária
Tipo: Trabalho de Conclusão de Curso
Publicado em 19/04/2010 Português
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Dissertação de Mestrado Integrado em Medicina Veterinária; A Demodecose Canina (DC) é uma dermatose parasitária inflamatória, resultante da proliferação anormal de ácaros Demodex canis nos folículos pilosos e glândulas sebáceas, associada a uma desregulação na resposta imunitária, que acomete frequentemente canídeos em idade juvenil. No cão, foram recentemente identificadas novas espécies de Demodex sp. (Demodex cornei e Demodex injai), todavia a sua patogenicidade e o seu grau de envolvimento no desenrolar desta doença, ainda está por determinar. Esta doença pode também afectar animais em idade adulta, estando nesse caso geralmente associada à co-existência de outras doenças sistémicas ou resultar da instituição de terapêuticas e/ou outros factores imunossupressores. Clinicamente a DC, é caracterizada por lesões de alopécia, eritema, hiperpigmentação, prurido variável, por vezes agravados com pápulas ou pústulas. Consoante a extensão das lesões, consideram-se duas entidades clínicas distintas, a Demodecose Localizada (DL) e a Demodecose Generalizada (DG). Enquanto a DL com uma evolução geralmente benigna, é na maioria dos casos auto-limitante, não necessitando portanto de tratamento específico...

‣ Demodex folliculorum on the eyelash follicule of diabetic patients

Yamashita,Letícia Satsiê Fátima de Freitas; Cariello,Angelino Julio; Geha,Nahin Mohamed Ali; Yu,Maria Cecilia Zorat; Hofling-Lima,Ana Luisa
Fonte: Conselho Brasileiro de Oftalmologia Publicador: Conselho Brasileiro de Oftalmologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2011 Português
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PURPOSE: To compare the prevalence of Demodex folliculorum on the eyelashes of patients with proliferative diabetic retinopathy and healthy voluntaries. METHODS: Type 2 diabetic patients with proliferative retinopathy and age- and gender-matched healthy voluntaries (group control) underwent a slit lamp examination which three eyelashes containing cylindrical dandruff were removed from each lid by fine forceps. The lashes were dyed with fluorescein and the presence of Demodex folliculorum was verified by direct visualization under a light microscope. The mites were recognized based on its morphology and peculiar movement. The results were expressed in "positive" when at least one mite on one lash was found and "negative" when no mite was identified. The Chi-square test was used for comparing mites' presence in both groups. RESULTS: Forty-two patients were included in each group. The age ranged from 50 to 60 years old, with a mean of 56.4 ± 5.2 years. The male:female ratio was 0.6:1. There was no statistically significant difference with regard to age and gender in both groups (p>0.05). Demodex folliculorum was significantly more prevalent in diabetic patients (54.8%) than in control patients (38.1%) (p=0.048). CONCLUSION: Demodex folliculorum was more prevalent in diabetic patients than in healthy voluntaries...

‣ Demodex y blefaritis crónica

Rodríguez,AE; Ferrer,C; Alió,JL
Fonte: Archivos de la Sociedad Española de Oftalmología Publicador: Archivos de la Sociedad Española de Oftalmología
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/11/2005 Português
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Propósito: Demodex es un ácaro encontrado con cierta frecuencia en los folículos pilosos y en las glándulas sebáceas de personas sanas. Debido a que este ácaro ha sido reportado además en muchos casos de blefaritis crónica quisimos conocer el índice de infestación de Demodex en personas sanas y en pacientes con blefaritis crónica, además de evaluar la respuesta a los diferentes tratamientos utilizados para tratar la blefaritis. Métodos: Se seleccionaron como grupo control 105 personas sin blefaritis y como pacientes 20 personas con blefaritis crónica. Las pestañas extraídas de ambos grupos fueron observadas al microscopio. Los pacientes con sobrepoblación de ácaros fueron tratados mediante limpieza de párpados y pestañas con éter y pomada de óxido amarillo de mercurio al 2%. Resultados: La incidencia de Demodex folliculorum en el grupo control fue de 0,08 ácaros/pestaña y en los pacientes con blefaritis crónica de 0,69 ácaros/pestaña, esta diferencia fue estadísticamente significativa (p=0,006). Todos los ácaros hallados fueron Demodex folliculorum exceptuando los de un paciente que se identificaron como Demodex brevis. Después de 3-8 semanas de tratamiento específico el número de ácaros por pestaña disminuyó drásticamente (índice de 0...

‣ Prevalencia de infección por Demodex folliculorum en pacientes que acuden a consulta general de oftalmología

Galvis-Ramírez,Virgilio; Tello-Hernández,Alejandro; Álvarez-Osorio,Leonardo; Rey-Serrano,Juan J.
Fonte: Instituto de Salud Publica, Faculdad de Medicina -Universidad Nacional de Colombia Publicador: Instituto de Salud Publica, Faculdad de Medicina -Universidad Nacional de Colombia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2011 Português
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27.988574%
Objetivos Determinar la prevalencia de infección por Demodex folliculorum en pacientes que asisten a consulta general de oftalmología, y su asociación con blefaritis. Métodos Estudio descriptivo de prevalencia. En forma aleatoria se seleccionaron 128 sujetos que asistieron al Centro Oftalmológico Virgilio Galvis y se determinó la presencia de Demodex folliculorum en 4 pestañas de cada uno. Resultados La prevalencia de infección por Demodex folliculorum fue 42,1 % (n= 54). Se diagnosticó blefaritis en el 38,3 % de los pacientes (n=49) y el 63,2 % de ellos (n=31) fueron positivos para D. folliculorum. En el grupo sin blefaritis (n=79) solo el 29,2 % de los individuos tenían el ácaro (n=23) (p=0.0003). Además se encontró una mayor cantidad de parásitos en los pacientes con blefaritis (índice de carga parasitaria 12,7 vs 5,1 (p=0.0001). El 25 % (n=32) de los participantes presentaban descamación en forma de cilindros y en estos el 96,9 % tenían el ácaro (n= 31), mientras que en los sujetos que no tenían cilindros (n=96) el ácaro estuvo presente solo en el 24 % (n=23). Conclusiones El Demodex folliculorum es un parásito que se encuentra en personas sin lesiones oculares, pero que es más frecuente y presenta una mayor carga parasitaria en pacientes con blefaritis. Nuestros resultados sugieren la necesidad de investigar la presencia de Demodex folliculorum en todo paciente con blefaritis y especialmente en los casos en que se observe presencia de descamación en forma de cilindros en las pestañas.