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‣ Colon Cancer Screening with Image-Enhanced Endoscopy

Ko, Bong Min
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Artigo de Revista Científica
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Colorectal cancer (CRC) is a major cause of cancer mortality worldwide, and this has led to an increased use of screening colonoscopy. This screening has resulted in long-term risk reduction in asymptomatic individuals. However, endoscopists may fail to detect advanced adenomas or colon cancer during screening. The reasons that adenomas or cancers are missed are thought to be associated with the location of the lesions or the skills of the endoscopist. To address the limitations of white light endoscopy (WLE) for adenoma detection, advanced endoscopic images have recently been used. Image-enhanced endoscopies (IEEs), including the use of topical dyes, optical filtering, and ultramagnification, allow for gastrointestinal lesion analysis. Many studies have compared the adenoma detection rate (ADR) obtained by using WLE and IEE, but with different results. IEE can be used to help the endoscopist to improve their ADR in screening colonoscopy. This review examines the possible roles of image-enhanced colonoscopy in CRC screening.

‣ Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions

Lee, Sang Kil
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of CLE are more obvious in esophageal disease, including Barrett’s esophagus. Currently, this technology has been adapted to the diagnosis and surveillance of Barrett’s esophagus and related neoplasia. Standard white light endoscopy is the primary tool for gastric cancer screening. Currently, the only method available to precisely diagnose these lesions is upper endoscopy with an appropriate biopsy. A recent study showed that CLE could characterize dysplasia or cancer and identify the risk factors for gastric cancer, such as intestinal metaplasia and the presence of Helicobacter pylori in vivo, although fewer studies on CLE were performed on the stomach than on Barrett’s esophagus and other esophageal diseases. However, the application of CLE to routine clinical endoscopy continues to be refined. This review focused on the usefulness and future prospects of CLE for gastric premalignant and malignant lesions.

‣ Polyp Detection, Characterization, and Management Using Narrow-Band Imaging with/without Magnification

Utsumi, Takahiro; Iwatate, Mineo; Sano, Wataru; Sunakawa, Hironori; Hattori, Santa; Hasuike, Noriaki; Sano, Yasushi
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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Narrow-band imaging (NBI) is a new imaging technology that was developed in 2006 and has since spread worldwide. Because of its convenience, NBI has been replacing the role of chromoendoscopy. Here we review the efficacy of NBI with/without magnification for detection, characterization, and management of colorectal polyps, and future perspectives for the technology, including education. Recent studies have shown that the next-generation NBI system can detect significantly more colonic polyps than white light imaging, suggesting that NBI may become the modality of choice from the beginning of screening. The capillary pattern revealed by NBI, and the NBI International Colorectal Endoscopic classification are helpful for prediction of histology and for estimating the depth of invasion of colorectal cancer. However, NBI with magnifying colonoscopy is not superior to magnifying chromoendoscopy for estimation of invasion depth. Currently, therefore, chromoendoscopy should also be performed additionally if deep submucosal invasive cancer is suspected. If endoscopists become able to accurately estimate colorectal polyp pathology using NBI, this will allow adenomatous polyps to be resected and discarded; thus, reducing both the risk of polypectomy and costs. In order to achieve this goal...

‣ Advanced Imaging Technology Other than Narrow Band Imaging

Cho, Jun-Hyung
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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To improve the detection rate of gastrointestinal tumors, image-enhanced endoscopy has been widely used during screening and surveillance endoscopy in Korea. In addition to narrow band imaging (NBI) with/without magnification, various types of electronic chromoendoscopies have been used, including autofluorescence imaging, I-scan, and flexible spectral imaging color enhancement. These technologies enable the accurate characterization of tumors because they enable visualization of microvascular and microsurface patterns. The present review focuses on understanding the principle and clinical applications of advanced imaging technologies other than NBI.

‣ Narrow Band Imaging: Technology Basis and Research and Development History

Gono, Kazuhiro
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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The first launch of narrow band imaging (NBI) was in 2005. Since then, in most countries where gastrointestinal endoscopies are performed, NBI is the most commonly used optical digital method of performing image-enhanced endoscopy. Thanks to the outstanding efforts of many endoscopists, many clinical studies have been performed and clinical evidence has been gathered. In Japan, since 2010, NBI has been reimbursed under the Japanese national health insurance system. This is owing to the establishment of clinical evidence by physicians. However, even though endoscope systems with NBI function have been widely used outside of Japan, dissemination of knowledge on how to use NBI is insufficient. In this review paper, the technology basis of NBI and its research and development history are described. I hope this information will be helpful for updating physicians’ knowledge of NBI.

‣ Clinical Application of Magnifying Endoscopy with Narrow-Band Imaging in the Stomach

Yao, Kenshi
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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Magnifying endoscopy with narrow-band imaging (M-NBI) can visualize superficial microanatomies in the stomach. The normal morphology of the microanatomy visualized by M-NBI differs according to the part of the stomach. The gastric fundic glandular mucosa appears as a regular honeycomb-like subepithelial capillary network (SECN) pattern with a regular collecting venule pattern and regular oval crypt opening with circular marginal crypt epithelium (MCE) pattern. The gastric pyloric glandular mucosa displays a regular coil-shaped SECN pattern and regular polygonal or curved MCE pattern. For a diagnosis of early gastric cancer using M-NBI, the vessel plus surface classification system was developed. This system is clinically useful for the differential diagnosis of focal gastritis and small depressed cancer and for determining the horizontal extent of early gastric cancer for successful endoscopic resection. Advantages of M-NBI over conventional endoscopic imaging techniques with white light include accurate diagnosis and cost effectiveness. This technique is a breakthrough in the endoscopic diagnostic field.

‣ Advanced Imaging Technology in Biliary Tract Diseases:Narrow-Band Imaging of the Bile Duct

Choi, Hyun Jong; Moon, Jong Ho; Lee, Yun Nah
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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Newly introduced direct peroral cholangioscopy and the development of video choledochoscopes have enabled more defined observation of bile duct mucosal lesions with clearer images. Narrow-band imaging (NBI) is a unique endoscopic imaging technology that provides enhanced endoscopic images of surface mucosal structures and its superficial microvessels. Advanced cholangioscopy and NBI are expected to be useful for precise evaluation and correct diagnosis of biliary tract diseases. However, the diagnostic value of advanced bile duct imaging with cholangioscopy requires further evaluation.

‣ The Past, Present, and Future of Image-Enhanced Endoscopy

Jang, Jae-Young
Fonte: The Korean Society of Gastrointestinal Endoscopy Publicador: The Korean Society of Gastrointestinal Endoscopy
Tipo: Text
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Despite the remarkable progress recently made to enhance the resolution of white-light endoscopy, detection, and diagnosis of premalignant lesions, such as adenomas and subtle early-stage cancers, remains a great challenge. As for example, although chromoendoscopy, such as endoscopy using indigo carmine, is useful for the early diagnosis of subtle lesions, the technique presents various disadvantages ranging from the time required for spray application of the dye and suctioning of excess dye to the increased difficulty in identifying lesions in the presence of severe inflammation and obstruction of visual field due to the pooling of solution in depressed-type lesions. To overcome these diagnostic problems associated with chromoendoscopy, research has focused on the development of endoscopes based on new optical technologies. Several types of image-enhanced endoscopy methods have recently been presented. In particular, image-enhanced endoscopy has emerged as a new paradigm for the diagnosis of gastrointestinal disorders. Image-enhanced endoscopes provide high-contrast images of lesions by means of optical or electronic technologies, including the contrast enhancement of the mucosal surface and of blood vessels. Chromoendoscopy, narrow-band imaging...