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‣ Nigerian Population Research on Environment, Gene and Health (NIPREGH) – objectives and protocol

Odili, Augustine N.; Ogedengbe, John O.; Nwegbu, Maxwell; Anumah, Felicia O.; Asala, Samuel; Staessen, Jan A
Fonte: Editorial Department of Journal of Biomedical Research Publicador: Editorial Department of Journal of Biomedical Research
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
55.66222%
Sub-Saharan Africa is currently undergoing an epidemiological transition from a disease burden largely attributable to communicable diseases to that resulting from a combination of both communicable and chronic non-communicable diseases. Data on chronic disease incidence, lifestyle, environmental and genetic risk factors are sparse in this region. This report aimed at providing relevant information in respect to risk factors that increase blood pressure and lead to development of intermediate cardiovascular phenotypes. We presented the rationale, objectives and key methodological features of the Nigerian Population Research on Environment, Gene and Health (NIPREGH) study. The challenges encountered in carrying out population study in this part of the world and the approaches at surmounting them were also presented. The preliminary data as at 20 November 2013 showed that out of the 205 individuals invited starting from early April 2013, 160 (72 women) consented and were enrolled; giving a response rate of 78%. Participants' age ranged from 18 to 80 years, with a mean (SD) of 39.8 (12.4) years and they were of 34 different ethnic groups spread over 24 states out of the 36 states that constitute Nigeria. The mean (SD) of office and home blood pressures were 113.0 (15.2) mm Hg systolic...