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‣ Weight loss during cirrhosis is related to the etiology of liver disease

Anastácio,Lucilene Rezende; Ferreira,Lívia Garcia; Ribeiro,Hélem de Sena; Lima,Agnaldo Soares; Vilela,Eduardo Garcia; Correia,Maria Isabel Toulson Davisson
Fonte: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia - IBEPEGE ; Colégio Brasileiro de Cirurgia Digestiva - CBCD ; Sociedade Brasileira de Motilidade Digestiva - SBMD ; Federação Brasileira de Gastroenterologia - FBG; Sociedade Brasileira de Hepatologia - SBH; Sociedade Brasileira de Endoscopia Digestiva - SOBED Publicador: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia - IBEPEGE ; Colégio Brasileiro de Cirurgia Digestiva - CBCD ; Sociedade Brasileira de Motilidade Digestiva - SBMD ; Federação Brasileira de Gastroenterologia - FBG; Sociedade Brasileira de Hepatologia - SBH; Sociedade Brasileira de Endoscopia Digestiva - SOBED
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2012 Português
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CONTEXT: Malnutrition is widely described in patients waiting for liver transplantation (LTx). However, risk factors associated with weight loss during liver disease have not yet been well studied. OBJECTIVES: The aim of this study was to assess weight loss and its risk factors during liver disease and up to the first appointment after transplantation. Patients who underwent LTx were retrospectively assessed for weight loss during liver disease while on the waiting list for LTx. The usual weight of the patients before disease and their weight on the first outpatient appointment after transplant were considered. Demographic, socioeconomic, lifestyle and clinical variables were collected to assess risk factors using a linear regression analysis. We retrospectively evaluated 163 patients undergoing LTx between 1997 and 2008. RESULTS: Patients lost in average 7.7 ± 12.4 kg while ill. Variables independently associated with weight loss by multiple linear regression analyses were as follows: former smoker (P = 0.03), greater body mass index (P<0.01), overweight before liver disease (P = 0.02) and indication for LTx (P = 0.01). Among these indications, patients with alcoholic cirrhosis had lost significantly more weight (P<0.01), and those with hepatitis C virus (P = 0.01) and autoimmune hepatitis (P = 0.02) had lost significantly less weight. CONCLUSIONS: Patients experienced weight loss during liver disease independent of age...

‣ Prevalence of weight-loss strategies and use of substances for weight-loss among adults: a population study

Machado,Eduardo Coelho; Silveira,Mariângela Freitas da; Silveira,Vera Maria Freitas da
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2012 Português
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This paper concerns a cross-sectional population-based study conducted with adults living in the city of Pelotas, Rio Grande do Sul State, Brazil. It aims to determine the prevalence of weight-loss practices and use of substances for weight-loss during the 12 months preceding the interview. The prevalence of weight-loss attempts was 26.6%. Although dietary control and regular physical exercise were the most commonly used strategies, the prevalence of the combined use of these methods was only 36% for individuals trying to lose weight. The prevalence of use of substances for weight-loss was 12.8% (48.4% of those who tried to lose weight). The use of dietary control and substances was more common among women, while men practiced physical exercise with greater frequency. Teas were the most frequently used substances for weight-loss. Multivariate analysis identified being female, excess weight and self-perception of excess weight as major associated factors for the use of substances for weight-loss. Finally, we found that, although weight-loss attempts are common, the majority of obese individuals do not make attempts to lose weight and only a minority follows the recommended practices.

‣ Preoperative weight loss in super-obese patients: study of the rate of weight loss and its effects on surgical morbidity

Santo,Marco Aurelio; Riccioppo,Daniel; Pajecki,Denis; Cleva,Roberto de; Kawamoto,Flavio; Cecconello,Ivan
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2014 Português
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OBJECTIVES: The incidence of obesity and particularly super obesity, has increased tremendously. At our institution, super obesity represents 30.1% of all severely obese individuals in the bariatric surgery program. In super obesity, surgical morbidity is higher and the results are worse compared with morbid obesity, independent of the surgical technique. The primary strategy for minimizing complications in these patients is to decrease the body mass index before surgery. Preoperative weight reduction can be achieved by a hypocaloric diet, drug therapy, an intragastric balloon, or hospitalization. The objective of this study was to analyze the results of a period of hospitalization for preoperative weight loss in a group of super-obese patients. METHODS: Twenty super-obese patients were submitted to a weight loss program between 2006 and 2010. The mean patient age was 46 years (range 21-59). The mean BMI was 66 kg/m2 (range 51-98) and 12 were women. The average hospital stay was 19.9 weeks and the average weight loss was 19% of the initial weight (7-37%). The average caloric intake was 5 kcal/kg/day. After the weight loss program...

‣ Depression, Stress and Weight Loss in Individuals with Metabolic Syndrome in SHINE, a DPP Translation Study

Trief, Paula M.; Cibula, Donald; Delahanty, Linda M.; Weinstock, Ruth S.
Fonte: Harvard University Publicador: Harvard University
Tipo: Artigo de Revista Científica
Português
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OBJECTIVE To examine the relationships between elevated depression symptoms (EDS) or stress and weight loss in SHINE, a telephonic, primary-care based, translation of the Diabetes Prevention Program. DESIGN AND METHODS N=257 adults with metabolic syndrome were randomized to individual (IC) or group (CC) phone participation. We assessed weight, depression, anti-depressant use (ADMs), and stress (baseline, 6 months, 1 and 2 years). Univariate analyses used linear and logistic regression, t-tests for continuous variables and exact tests for categorical variables. Stratified analyses assessed modifiers of effects of depression/stress on weight loss. RESULTS Approximately 35% reported EDS, with no change over time. Approximately 28% of all participants used ADMs. Participants with EDS had lower mean % weight loss and a smaller % who achieved ≥ 5% weight loss. Participants with EDS were less likely to be “completers” (40.1 % vs. 61.5%, p=.002), coached (48.0% vs. 60.7%, p=.049), or log diet/activity (19.4% vs. 42.7%, p<.001), behaviors related to weight loss. Results were similar for high stress. ADM use had no independent effect on weight loss. CONCLUSIONS Individuals with metabolic syndrome and EDS and/or high stress were less likely to lose significant weight. Pre-intervention depression and stress screening to intervene may improve weight loss.

‣ Short-term meal replacements followed by dietary macronutrient restriction enhance weight loss in polycystic ovary syndrome

Moran, L.; Noakes, M.; Clifton, P.; Wittert, G.; Williams, G.; Norman, R.
Fonte: Amer Soc Clinical Nutrition Publicador: Amer Soc Clinical Nutrition
Tipo: Artigo de Revista Científica
Publicado em //2006 Português
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BACKGROUND: Polycystic ovary syndrome (PCOS), a common condition in women, improves with weight loss. Meal replacements in short-term weight loss and strategies for weight maintenance have not been investigated in PCOS. OBJECTIVE: We compared in overweight women with PCOS the effects of meal replacements in short-term weight-loss and longer-term carbohydrate- or fat-restriction strategies on weight maintenance and improvements in reproductive and metabolic variables. DESIGN: Overweight women with PCOS (n = 43; x +/- SD age: 32.1 +/- 5.2 y; weight: 96.1 +/- 18.4 kg) followed an 8-wk weight-loss regimen (2 meal replacements/d, 4904.4 +/- 127 kJ; phase 1) and then a 6-mo weight-maintenance carbohydrate- (<120 g/d) or fat- (<50 g/d) restriction regimen (phase 2). RESULTS: Thirty-four women completed phase 1, and 23 women completed phase 2; the proportion of dropouts was similar in the 2 groups. During phase 1, significant (P < 0.05) reductions in weight (5.6 +/- 2.4 kg), waist circumference (6.1 +/- 2.5 cm), body fat (4.1 +/- 2.2 kg), insulin (2.8 +/- 1.1 mU/L), total testosterone (0.3 +/- 0.7 nmol/L), and free androgen index (3.1 +/- 4.6) occurred; these changes were sustained during phase 2. No significant differences between diet groups were seen for any variables. At 6 mo...

‣ Effects of weight loss on a low-carbohydrate diet on flow-mediated dilatation, adhesion molecules and adiponectin

Keogh, J.; Brinkworth, G.; Clifton, P.
Fonte: C A B I Publishing Publicador: C A B I Publishing
Tipo: Artigo de Revista Científica
Publicado em //2007 Português
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Our aim was to determine whether short-term weight loss on a low-carbohydrate/low-saturated fat diet improved endothelial function compared with a conventional high-carbohydrate diet, as this diet is expected to lower both blood glucose and LDL-cholesterol. In a randomised parallel design of two energy-restricted diets in an outpatient setting, thirty-six subjects (BMI 33 (sem 4) kg/m2) were randomised to a low- or high-carbohydrate diet both low in saturated fat. Flow-mediated dilatation (FMD), fasting glucose, insulin, lipids, adiponectin and adhesion molecules were measured at baseline, during weight loss and at 52 weeks. FMD did not change with either diet (5·2 (sem 0·6) to 5·5 (sem 0·6) %) despite weight loss of 5 % and significant reductions in glucose and insulin and LDL-cholesterol and was not different after sustained weight loss of 5 % at 52 weeks. Adiponectin fell by 6 % at 12 weeks (P = 0·1) with weight loss but rose by 17 % at 12 months (P < 0·05) with 5 % weight loss. There were no effects of diet. In contradistinction, adhesion molecules fell at 12 weeks, vascular cell adhesion molecule-1 by 14 % and intracellular adhesion molecule-1 by 13 % (both P < 0·05). There were correlations between change in adiponectin at 12 months and change in HDL (r 0·778...

‣ C-reactive protein before and after weight loss in overweight women with and without polycystic ovary syndrome

Moran, L.; Noakes, M.; Clifton, P.; Wittert, G.; Belobrajdic, D.; Norman, R.
Fonte: Endocrine Society Publicador: Endocrine Society
Tipo: Artigo de Revista Científica
Publicado em //2007 Português
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BACKGROUND: Polycystic ovary syndrome (PCOS) is associated with reproductive and metabolic abnormalities. It is unknown whether overweight women with and without PCOS achieve similar benefits from weight loss for cardiovascular risk factors. METHOD: Overweight body mass index-matched women with (n = 15) and without (n = 17) PCOS (weight, 95.3 +/- 17.6 kg; body mass index, 35.6 +/- 5.3 kg/m(2), mean +/- sd) followed an 8-wk weight loss regime. RESULTS: All subjects had similar reductions in weight (3.9 +/- 3.6 kg, 3.8%, vs. 4.5 +/- 4.1 kg, 4.7%, respectively, for PCOS and non-PCOS), waist circumference, fat mass, triglycerides, free testosterone, and fasting and postprandial insulin. At baseline, C-reactive protein (CRP) between groups was not significantly different (5.5 +/- 3.1 mg/liter for PCOS vs. 4.9 +/- 3.0 mg/liter for non-PCOS). There was a significant interaction between PCOS status and CRP (P = 0.016) such that CRP decreased with weight loss for non-PCOS women (-1.2 +/- 1.8 mg/liter; P = 0.025) but not for PCOS women. For all women, the change in CRP correlated with the change in weight (r = 0.560; P = 0.003), fat mass (r = 0.477; P = 0.016), and postprandial insulin (r = 0.402; P = 0.046). Adiponectin, IL-6, and TNF-alpha were not significantly different between groups before or after weight loss. Only subjects with baseline CRP levels below the median (4.52 mg/liter) showed increases in adiponectin (0.98 +/- 1.3 microg/liter) (P = 0.015) and greater reductions in triglycerides (P = 0.001) with weight loss. CONCLUSION: A 4-5% weight loss improved lipid...

‣ The use of anti-mullerian hormone in predicting menstrual response after weight loss in overweight women with polycystic ovary syndrome

Moran, L.; Noakes, M.; Clifton, P.; Norman, R.
Fonte: Endocrine Society Publicador: Endocrine Society
Tipo: Artigo de Revista Científica
Publicado em //2007 Português
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BACKGROUND: Polycystic ovary syndrome (PCOS) is associated with reproductive and metabolic abnormalities, specifically menstrual dysfunction and anovulation in conjunction with elevated pre-antral follicle number and arrested follicular maturation. Although anti-müllerian hormone (AMH), an inhibitor of follicle recruitment and maturation, is increased in women with PCOS, the usefulness of circulating AMH levels as a clinical predictor of menstrual response to weight loss in PCOS is not known. METHODS: Overweight women with PCOS (n = 26, age 32.9 +/- 5.8 yr, weight 98.9 +/- 20.8 kg, body mass index 36.1 +/- 7.0 kg/m(2), mean +/- sd) followed an 8-wk weight loss and 6-month weight maintenance program. RESULTS: Net reductions in weight (4.6 +/- 4.8 kg), waist circumference (6.0 +/- 5.3 cm), testosterone (0.3 +/- 0.6 nmol/liter), fasting insulin (3.7 +/- 7.6 mU/liter), and the homeostasis model assessment of insulin sensitivity (0.7 +/- 1.3) occurred for all subjects over the entire study duration. Of 26 subjects, 15 (57.7%) responded to the intervention with improvements in menstrual cyclicity (responders). Compared to nonresponders, responders had lower AMH levels at baseline (23.6 +/- 12.0 vs. 37.9 +/- 17.8 pmol/liter; P = 0.021). Only responders had reductions in fasting insulin (6.1 +/- 5.9 mU/liter; P = 0.001) and homeostasis model assessment (1.3 +/- 5.9; P = 0.002) with acute weight loss (wk 0-8). Baseline AMH was most strongly predicted by baseline ghrelin...

‣ Long-term effects of a high-protein weight-loss diet

Clifton, P.; Keogh, J.; Noakes, M.
Fonte: Amer Soc Clinical Nutrition Publicador: Amer Soc Clinical Nutrition
Tipo: Artigo de Revista Científica
Publicado em //2008 Português
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Background: Evidence that high-protein diets are an effective strategy for the maintenance of long-term weight loss is limited. Objective: The objective was to determine the efficacy of a higher protein intake on the maintenance of weight loss after 64 wk of follow-up. Design: Seventy-nine healthy women with a mean (±SD) age of 49 ± 9 y and a body mass index (in kg/m2) of 32.8 ± 3.5 completed an intensive 12-wk weight-loss program and 52 wk of follow-up to compare the effects on weight-loss maintenance of a high-protein (HP) diet (34% of energy) or a high-carbohydrate (HC) diet (64% of energy). Results: Mean (±SD) weight loss was not significantly different between groups: (HP: 4.6 ± 5.5 kg; HC: 4.4 ± 6.1 kg). Protein intake (g) from dietary records at 64 wk was directly related to weight loss (P < 0.0001), accounting for 15% of the variance. Protein intake as a percentage of energy was also related to weight change (P = 0.003), accounting for 10% of the variance. In the upper tertile (88 g protein/d), weight loss was 6.5 ± 7.5 and 3.4 ± 4.4 kg (P = 0.03) in the 2 lower tertiles, respectively. This difference did not translate to a difference in central fat loss between groups. Lipids, glucose, insulin, C-reactive protein...

‣ The effect of weight loss on anti-Müllerian hormone levels in overweight and obese women with polycystic ovary syndrome and reproductive impairment; The effect of weight loss on anti-Mullerian hormone levels in overweight and obese women with polycystic ovary syndrome and reproductive impairment

Thomson, R.; Buckley, J.; Moran, L.; Noakes, M.; Clifton, P.; Norman, R.; Brinkworth, G.
Fonte: Oxford Univ Press Publicador: Oxford Univ Press
Tipo: Artigo de Revista Científica
Publicado em //2009 Português
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BACKGROUND: Anti-Müllerian hormone (AMH) has been proposed as a clinical predictor of improvements in reproductive function following weight loss in overweight and obese women with polycystic ovary syndrome (PCOS). This study aimed to assess whether baseline and/or change in AMH levels with weight loss predict improvements in reproductive function in overweight and obese women with PCOS. METHODS: Fifty-two overweight and obese women with PCOS and reproductive impairment (age 29.8 +/- 0.8 years, BMI 36.5 +/- 0.7 kg/m(2)) followed a 20-week weight loss programme. AMH, weight, menstrual cyclicity and ovulatory function were assessed at baseline and post-intervention. RESULTS: Participants who responded with improvements in reproductive function (n = 26) had lower baseline AMH levels (23.5 +/- 3.7 versus 32.5 +/- 2.9 pmol/l; P = 0.03) and experienced greater weight loss (-11.7 +/- 1.2 versus -6.4 +/- 0.9 kg; P = 0.001) compared with those who did not respond (n = 26). Logistic regression analysis showed that weight loss and baseline AMH were independently related to improvements in reproductive function (P = 0.002 and P = 0.013, respectively). AMH levels did not change with weight loss in both responders and non-responders. CONCLUSIONS: In overweight and obese women with PCOS and reproductive dysfunction...

‣ Reductions in blood pressure following energy restriction for weight loss do not rebound after re-establishment of energy balance in overweight and obese subjects

Brinkworth, G.; Wycherley, T.; Noakes, M.; Clifton, P.
Fonte: Marcel Dekker Inc Publicador: Marcel Dekker Inc
Tipo: Artigo de Revista Científica
Publicado em //2008 Português
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OBJECTIVE: The objective of the present study was to elucidate the separate effects of energy restriction and weight loss on blood pressure (BP) and to assess the relationship between sodium intake, weight loss, and BP. METHODS: Two hundred and eight overweight and obese subjects (age: 52.4 +/- 0.8 yrs; BMI 33.6 +/- 0.3 kg/m(2)) completed a weight loss diet program consisting of 8-12 weeks of moderate energy restriction (ER; approximately 30% energy deficit, unrestricted salt intake) and four weeks of energy balance (EB). Body weight and BP were measured at baseline, the midpoint, and the end of ER and after EB. 24-hr Na+ excretion was measured at baseline and at the end of EB. RESULTS: Overall, body weight reduced progressively by 7.0 +/- 0.2 kg (7.5%; p < 0.001) with the hypocaloric diet. BP fell substantially during the first phase of ER (-5.7 +/- 0.7/-2.6 +/- 0.4 mmHg, p = 0.001), corresponding to a 4.5 +/- 0.2 kg weight reduction, with no further BP changes during the second phase of ER, despite further weight loss (2.4 +/- 0.1 kg). During EB, BP remained stable. The hypotensive effects of caloric restriction and weight loss were similar across clinical subgroups defined by age, sex, diabetes, insulin sensitivity, and hypertensive status. BP responses to weight loss were independent of 24-hr urinary Na+ excretion. 24-hr urinary Na+ excretion was similar at baseline and at the end of EB (146.5 +/- 5.3 vs. 146.9 +/- 5.3 mmol/24-hr). CONCLUSION: The hypotensive effects of caloric restriction do not rebound upon return to eucaloric intake at a reduced body weight...

‣ The impact of high protein-high red meat vs high carbohydrate weight loss diets on genome stability and biomarkers of colorectal cancer risk in overweight men.

Benassi, Bianca Jane
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2008 Português
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It has been suggested that high protein diets are associated with an increased risk of colorectal cancer due to the higher content of red meat. However, the study of the overall dietary and lifestyle pattern may prove more important than any individual component when assessing colorectal cancer risk. From this, it is proposed that a dietary pattern used for weight loss that is higher in protein but remains low in fat and high in foods rich in fibre and micronutrients that are required for genome stability may not increase the risk of colorectal cancer, thus providing a safe and effective dietary method of weight loss in overweight subjects. This thesis describes the development of a novel in vitro faecal water genotoxicity test using the cytokinesis-block micronucleus (CBMN) cytome assay in the WIL2-NS cell line. This thesis then investigates faecal water genotoxicity and peripheral blood lymphocyte genome stability in overweight men following a weight loss dietary pattern either high in protein, specifically red meat, or high in carbohydrate. Results from this thesis indicate that the genotoxic potential of faecal water can be successfully assessed in vitro using the CBMN cytome assay. A high protein-high red meat weight loss diet did not increase faecal water genotoxicity or peripheral blood lymphocyte DNA damage...

‣ High-protein/high red meat and high-carbohydrate weight-loss diets do not differ in their effect on faecal water genotoxicity tested by use of the WIL2-NS cell line and with other biomarkers of bowel health

Benassi-Evans, B.; Clifton, P.; Noakes, M.; Fenech, M.
Fonte: Elsevier Science BV Publicador: Elsevier Science BV
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
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The impact of popular weight-loss diets with different macronutrient profiles on bowel health in humans has not been previously assessed. The aim of this study was to investigate whether a high-protein/high red meat (HP) diet influences faecal water genotoxicity and other standard biomarkers of bowel health differently compared with a high-carbohydrate (HC) diet. Thirty-three male subjects were randomly assigned to a HP (35% protein, 40% carbohydrate) or HC (17% protein, 58% carbohydrate) isocaloric energy-restricted dietary intervention consisting of 12 weeks intensive weight loss followed by weight maintenance for up to 52 weeks. Faecal samples were collected at 0, 12 and 52 weeks. Faecal water genotoxicity was assessed in the WIL2-NS human B lymphoblastoid cell line by means of the cytokinesis-block micronucleus cytome assay. Average weight loss after 12 weeks was 9.3 ± 0.7kg for both diets, with no further change in weight at 52 weeks. Two-way ANOVA showed a significant effect with time (P<0.001) but not diet for total DNA damage, with a reduction in genotoxicity after 12 weeks intensive weight loss, and a subsequent increase after 9 months weight maintenance to levels not significantly different from baseline. There was no significant effect for time or diet on faecal pH...

‣ Weight-loss induced changes in physical activity and activity energy expenditure in overweight and obese subjects before and after energy restriction

Bonomi, A.G.; Soenen, S.; Goris, A.H.C.; Westerterp, K.R.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
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Activity energy expenditure (AEE) is the component of daily energy expenditure that is mainly influenced by the amount of physical activity (PA) and by the weight of the body displaced. This study aimed at analyzing the effect of weight loss on PA and AEE. The body weight and PA of 66 overweight and obese subjects were measured at baseline and after 12 weeks of 67% energy restriction. PA was measured using a tri-axial accelerometer for movement registration (Tracmor) and quantified in activity counts. Tracmor recordings were also processed using a classification algorithm to recognize 6 common activity types engaged in during the day. A doubly-labeled water validated equation based on Tracmor output was used to estimate AEE. After weight loss, body weight decreased by 13±4%, daily activity counts augmented by 9% (95% CI: +2%, +15%), and this increase was weakly associated with the decrease in body weight (R(2) = 7%; P<0.05). After weight loss subjects were significantly (P<0.05) less sedentary (-26 min/d), and increased the time spent walking (+11 min/d) and bicycling (+4 min/d). However, AEE decreased by 0.6±0.4 MJ/d after weight loss. On average, a 2-hour/day reduction of sedentary time by increasing ambulatory and generic activities was required to restore baseline levels of AEE. In conclusion...

‣ Teenage girls’ first-person narratives about weight perception and dangerous weight loss practices: A study of five blogs from LiveJournal.com

Moscovitch, Erica Raina
Fonte: Quens University Publicador: Quens University
Tipo: Tese de Doutorado
Português
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In Western cultures, social significations are associated with body weight and shape (Woolf, 1990, as cited by Malson, 1998). Thinness is especially valued and especially for women and girls. As a result, many teenage girls aim to be thinner. This thesis examines five blogs on the website LiveJournal that are written by teenage girls who perceive themselves as overweight and who use blogs to talk about their attempts to lose weight. All five of these girls say that they practice at least one extreme method of weight loss and all of them have dangerously low weight loss goals. Two research questions motivated this study: 1) how do teenage girls who perceive themselves as overweight use blogs in their journeys to lose weight? 2) Can LiveJournal, or any other personal blogging site, provide a useful source for researchers so that they can learn about eating disorders in girls’ own words? The blogs provided a tool by which I could discover first-hand experiences of teenage girls who are trying to lose weight. Essentially, the blogs were used as both the data and the mean by which the data was collected. My results suggest that girls rarely discuss their weight loss practices with family or friends and thus their blogs provide a space where they can share their experiences and receive support and encouragement from other members of their online community who will not judge or stigmatize them. The results of this study are useful for social science researchers in two ways. First...

‣ In-hospital weight loss, prescribed diet and food acceptance

LEANDRO-MERHI,Vania Aparecida; SREBERNICH,Silvana Mariana; GONÇALVES,Gisele Mara Silva; AQUINO,José Luiz Braga de
Fonte: Colégio Brasileiro de Cirurgia Digestiva Publicador: Colégio Brasileiro de Cirurgia Digestiva
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2015 Português
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BACKGROUND: Weight loss and malnutrition may be caused by many factors, including type of disease and treatment. AIM: The present study investigated the occurrence of in-hospital weight loss and related factors. METHOD: This cross-sectional study investigated the following variables of 456 hospitalized patients: gender, age, disease, weight variation during hospital stay, and type and acceptance of the prescribed diet. Repeated measures analysis of variance (ANOVA) was used for comparing patients' weight in the first three days in hospital stay and determining which factors affect weight. The generalized estimating equation was used for comparing the food acceptance rates. The significance level was set at 5%. RESULTS: The most prescribed diet was the regular (28.8%) and 45.5% of the patients lost weight during their stay. Acceptance of hospital food increased from the first to the third days of stay (p=0.0022) but weight loss was still significant (p<0.0001). Age and type of prescribed diet did not affect weight loss during the study period but type of disease and gender did. Patients with neoplasms (p=0.0052) and males (p=0.0002) lost more weight. CONCLUSION: Weight loss during hospital stay was associated only with gender and type of disease.

‣ CLOCK 3111 T/C SNP Interacts with Emotional Eating Behavior for Weight-Loss in a Mediterranean Population

López Guimerà, Gemma; Dashti, Hassan S.; Smith, Caren E.; Sánchez Carracedo, David; Ordovas, José M.; Garaulet Aza, Marta
Fonte: Universidade Autônoma de Barcelona Publicador: Universidade Autônoma de Barcelona
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em //2014 Português
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Objective: The goals of this research was (1) to analyze the role of emotional eating behavior on weight-loss progression during a 30-week weight-loss program in 1,272 individuals from a large Mediterranean population and (2) to test for interaction between CLOCK 3111 T/C SNP and emotional eating behavior on the effectiveness of the weight-loss program. Design and Methods: A total of 1,272 overweight and obese participants (BMI: 31±5 kg/m2), aged 20 to 65 years, attending outpatient weight-loss clinics were recruited for this analysis. Emotional eating behavior was assessed by the Emotional Eating Questionnaire (EEQ), a questionnaire validated for overweight and obese Spanish subjects. Anthropometric measures, dietary intake and weight-loss progression were assessed and analyzed throughout the 30-week program. Multivariate analysis and linear regression models were performed to test for gene-environment interaction. Results: Weight-loss progression during the 30-week program differed significantly according to the degree of emotional eating behavior. Participants classified as ‘very emotional eaters’ experienced more irregular (P = 0.007) weight-loss, with a lower rate of weight decline (−0.002 vs. −0.003, P<0.05) in comparison with less emotional eaters. The percentage of weight-loss was also significantly higher in ‘non-emotional eaters’ (P = 0.009). Additionally...

‣ Postoperative Depression, Eating Behaviors, and Physical Activity as Indicators of Weight Loss in Gastric Bypass Patients

Martinez, Erin Elena
Fonte: Universidade Duke Publicador: Universidade Duke
Tipo: Dissertação
Publicado em //2014 Português
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67.34758%

Background: Bariatric surgery produces marked weight loss and improvement in comorbid health conditions among individuals with Class II or Class III obesity (Class I = 30.0 ≤ BMI ≤ 34.9kg/m2; Class II = 35.0 ≤ BMI ≥ 39.9kg/m2; Class III = BMI ≥ 40 kg/m2). However, suboptimal weight outcomes occur in a significant minority of patients. Evidence suggests that psychological and behavioral factors might affect weight loss, but most of the literature has focused on preoperative factors, with mixed results. The current study tested the hypothesis that postoperative depressive symptoms, eating behaviors, and lower levels of physical activity would be associated with poorer weight loss outcomes. Method: Preoperative data were obtained from an extant clinical database, and postoperative data were collected via a mail or online questionnaire in a sample of 141 female Roux-en-y gastric bypass (RYGB) patients at an average of 16.80 (SD=2.20) months post-surgery. Self-report measures assessed cognitive-affective and somatic symptoms of depression; binge eating, grazing, night eating, distress about overeating or loss of control over eating; and physical activity. Results: Weight outcome measures were defined as percentage of excess BMI loss (%EBMIL) and successful weight loss (≥ 50% EBMIL). Higher distress was associated with poorer %EBMIL...

‣ A Mobile Health Intervention to Sustain Recent Weight Loss

Shaw, Ryan J.
Fonte: Universidade Duke Publicador: Universidade Duke
Tipo: Dissertação
Publicado em //2012 Português
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Background: Obesity is the number one health risk facing Americans. The obesity epidemic in America is attributed to physical inactivity, unhealthy food choices, and excessive food intake. Structured weight loss programs have been successful in initiating behavior change and weight loss; however, weight is almost always regained over time. The rate of weight gain is highest immediately after cessation of a structured weight loss program. Thus, effective interventions are needed that can successfully be used following a structured weight loss program to sustain weight loss and prevent weight relapse. Due to low cost, ubiquity, and ease of use, healthcare communicated through mobile technology, or "mHealth", may be able to serve as an effective medium to reach a large number of people to facilitate weight loss behaviors. Short message service (SMS), also known as text messaging, is easy to use, ubiquitous, affordable, and can target people directly where they are regardless of geographic location, socioeconomic status, or demographic factors. A review of the literature demonstrated limited information regarding message content, timing and frequency of message delivery and only 3 of 14 SMS-related interventions reviewed demonstrated a statistically significant effect on weight loss...

‣ Prevalence of weight-loss strategies and use of substances for weight-loss among adults: a population study

Machado,Eduardo Coelho; Silveira,Mariângela Freitas da; Silveira,Vera Maria Freitas da
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2012 Português
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This paper concerns a cross-sectional population-based study conducted with adults living in the city of Pelotas, Rio Grande do Sul State, Brazil. It aims to determine the prevalence of weight-loss practices and use of substances for weight-loss during the 12 months preceding the interview. The prevalence of weight-loss attempts was 26.6%. Although dietary control and regular physical exercise were the most commonly used strategies, the prevalence of the combined use of these methods was only 36% for individuals trying to lose weight. The prevalence of use of substances for weight-loss was 12.8% (48.4% of those who tried to lose weight). The use of dietary control and substances was more common among women, while men practiced physical exercise with greater frequency. Teas were the most frequently used substances for weight-loss. Multivariate analysis identified being female, excess weight and self-perception of excess weight as major associated factors for the use of substances for weight-loss. Finally, we found that, although weight-loss attempts are common, the majority of obese individuals do not make attempts to lose weight and only a minority follows the recommended practices.