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‣ Padrão facial na dentadura decídua: estudo epidemiológico; Facial pattern in the deciduous dentition: epidemiologic study

SILVA FILHO, Omar Gabriel da; HERKRATH, Fernando José; QUEIROZ, Ana Paula Corrêa de; AIELLO, Carlos Alberto
Fonte: Dental Press Editora Publicador: Dental Press Editora
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
46.9306%
INTRODUÇÃO: é possível definir a morfologia facial e o padrão de crescimento em idade precoce, a partir da dentadura decídua completa. OBJETIVOS: frente à escassez de trabalhos na literatura pertinente ao assunto, a presente pesquisa explora o diagnóstico epidemiológico da face no estágio de dentadura decídua. METODOLOGIA: a amostra foi composta por 2.009 crianças de etnia brasileira, de ambos os gêneros, entre 3 e 6 anos de idade, no período de dentadura decídua completa, de 20 pré-escolas do município de Bauru/SP. RESULTADOS E CONCLUSÕES: baseando-se nos resultados obtidos no levantamento epidemiológico, foi encontrado - na análise em norma lateral - predomínio de crianças Padrão I (63,22%) em relação ao Padrão II (33,10%) e Padrão III (3,68%), não havendo diferenças estatisticamente significativas quanto ao gênero. Na análise em norma frontal, houve predomínio do tipo mesofacial (64,56%) em relação ao dolicofacial (21,90%) e braquifacial (13,54%), sendo que a proporção do tipo braquifacial nas meninas foi significativamente superior em relação aos meninos. Na distribuição dos tipos faciais frontais dentro dos padrões faciais sagitais ficou evidenciada uma manifestação mais freqüente do tipo dolicofacial dentro dos Padrões II e III...

‣ Estudo epidemiológico da dengue no período de 2000 a 2005 no Município de Guarulhos (SP); Epidemiologic study of dengue in the period of 2000 to 2005 in the city of Guarulhos (SP)

Mansho, Wilson
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 23/11/2006 Português
Relevância na Pesquisa
46.983984%
A cada ano a dengue tem preocupado cada vez mais os países e levado os sistemas de vigilância da saúde, nas diversas esferas, a adotar várias medidas para o seu controle, tendo em vista a iminência de uma grande epidemia de febre hemorrágica no mundo. Os estudos epidemiológicos ajudam esses sistemas de vigilância a melhorar e direcionar as ações preventivas para o controle da doença. O objetivo desse trabalho foi realizar um estudo epidemiológico dos casos notificados e confirmados de dengue, a partir do banco de dados do SINAN, nos anos de 2000 a 2005 no Município de Guarulhos (SP). Para se analisar a ocorrência da doença segundo variáveis sócio-demográficas (sexo, raça, faixa etária e a densidade demográfica de cada bairro) foi realizada uma análise estatística onde se observou as diferenças entre os casos do banco de dados e os indivíduos da população do município para cada variável. Para a variável sexo, não foram observadas diferenças estatísticas significativas entre as proporções para cada sexo na amostra e na população do município (P=0,28); para a variável raça, não foi observada diferença estatística significativa entre as proporções de indivíduos das raças parda e indígena (P>0...

‣ Epidemiologic study of anisometropia in students of Natal, Brazil

Garcia,Carlos Alexandre de Amorim; Dantas,Erymar de Araújo; Souza,Araken Britto de; Uchoa,Raquel Araújo Costa; Oréfice,Fernando
Fonte: Conselho Brasileiro de Oftalmologia Publicador: Conselho Brasileiro de Oftalmologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/2005 Português
Relevância na Pesquisa
46.78937%
PURPOSE: To perform an epidemiologic study in students in Natal/Brazil, with relation to refractional anisometropia, evaluating criteria such as: gender, age, and association with strabismus and amblyopia. METHODS: A study of 1,024 students randomly selected from several districts of Natal/Brazil was undertaken by the Department of Ophthalmology of the Federal University of Rio Grande do Norte (UFRN), observing the following criteria of > 2 spherical or cylindrical diopter refractional anisometropia relating it to sex, age, association with strabismus, amblyopia and anisometropia classification. RESULTS: We found a prevalence of 2% (N=21) anisometropia in the students. The female gender predominated with 81% (N=17). In students with anisometropia, we observed an association with strabismus in 9.5% of cases (N=2), both with exotropia. The association of anisometropia with amblyopia occurred in 47.6% of the cases (N=10), with 8 cases of unilateral amblyopia and 2 cases of bilateral amblyopia. CONCLUSIONS: There was a predominance of anisometropia in females, and an increased prevalence of strabismus and amblyopia in students with anisometropia.

‣ A clinical epidemiologic study in a schistosomiasis mansoni endemic area (Tuparecê, Minas Gerais)

Guimarães,Mark D. C.; Barros,Hélio L. de; Katz,Naftale
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/1985 Português
Relevância na Pesquisa
46.735986%
A population-based clinical epidemiologic study on schistosomiasis mansoni was carried out in Tuparecê, Minas Gerais. The patients were interviewed for symptoms, water contact, past history and examined for spleen and liver enlargement. From the 830 people registered in the census, 777 (93.6%) had their stools examined (Kato-Katz method) and 696 (83.9%) were clinically evaluated. The overall index of Schistosoma mansoni infection was 43.2%. Significant and increased infection risks could be detected in the young age group (2-14 years old) regarding occupation, time of residence in the area and frequency of water contact. Bloody stools were significantly more prevalent among positives, while diarrhea was significantly more prevalent among those negative. The area was shown to have a low morbidity as well as a low intensity of infection measured by the number of S. mansoni eggs per gram of feces. A close correlation was found between water contact pattern and the age prevalence curve. It has emphasized the importance of habits in determining prevalence rates, besides suggesting that schistosomiasis mansoni in the area is manifested as a light and somewhat harmless infection with little consequence for the population as a whole.

‣ Clinical-epidemiologic study of schistosomiasis mansoni in Ponte do Pasmado, a village in the municipality of Itinga, State of Minas Gerais, Brazil, 1992

Rodrigues,Rogéria Nobre; Murta,Cláudia; Teixeira Júnior,Marcos Aurélio Cota; Cury,Geraldo Cunha; Rocha,Manoel Otávio da Costa
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/1995 Português
Relevância na Pesquisa
46.735986%
A clinical-epidemiologic study of schistosomiasis mansoni was conducted in the population of Ponte do Pasmado, a village in the municipality of Itinga, state of Minas Gerais, Brazil. Faecal Parasitology by the Kato-Katz method and clinical examination were performed in 93.8% and 82.8% of the local population, respectively. A socioeconomic survey was also made and the signs and symptoms presented by the patients were recorded, as well as their contacts with natural waters. The rate of Schistosoma mansoni infection was 50.3%; the peak of infection occurred during the second decade of life; there was a predominance of low egg counts in faeces (85.89% of positive patients eliminated less than 500 eggs per gram of faeces); the splenomegaly rate was 1.23%. When the risk factors for S. mansoni infection were studied, significant risks were detected in activities such as fetching water, washing dishes, bathing, and crossing streams.

‣ Restriction endonuclease analysis of human and bovine group B streptococci for epidemiologic study.

Denning, D W; Baker, C J; Troup, N J; Tompkins, L S
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /06/1989 Português
Relevância na Pesquisa
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Group B streptococci, a frequent cause of neonatal sepsis and meningitis, postpartum endometritis, and bovine mastitis, may be acquired by several modes of transmission. Detailed epidemiologic study is hampered by the lack of a sufficiently discriminatory typing system, especially for type III and nontypable strains. We examined 54 epidemiologically well-characterized strains by restriction endonuclease analysis (REA) and compared the results with those obtained by serotyping. REA patterns were inspected without knowledge of the epidemiological or serotyping data. Among 21 type Ia, Ia/c, and Ib/c isolates, we found 10 REA patterns; among 5 type II and IIc isolates, we found 5 REA patterns; among 13 type III isolates, we found 6 REA patterns; and among 15 nontypable human and animal isolates, we found 7 different REA patterns. Double digestion of type III isolates with EcoRI and BglII helped us to distinguish the isolates. In total, 28 REA patterns were found in six serotype groups and one nontypable group. Some geographically and epidemiologically separate isolates had identical REA patterns, suggesting dissemination of a limited number of clones. We conclude that REA is a promising tool for detailed epidemiological study of group B streptococci.

‣ Chromosomal DNA fingerprint patterns produced with IS6110 as strain-specific markers for epidemiologic study of tuberculosis.

Mazurek, G H; Cave, M D; Eisenach, K D; Wallace, R J; Bates, J H; Crawford, J T
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /09/1991 Português
Relevância na Pesquisa
46.735986%
Mycobacterium tuberculosis isolates were studied by comparing chromosomal DNA fingerprint patterns produced by digestion of chromosomal DNA with BamHI, followed by agarose electrophoresis and hybridization with radiolabeled probes of insertion sequence IS6110. DNA fingerprints of 14 isolates from separate members of five households or closely associated individuals were compared. Marked differences were observed when unrelated isolates were compared. There were no or minimal differences in the restriction fragment patterns generated from isolates of any one household or associated group. Among related isolates, the only noticeable difference was an additional fragment of IS6110 in the fingerprint pattern of one isolate. Insertional activity was also suggested when restriction fragment patterns of H37Rv DNA isolated in 1987 and 1990 were compared. In a similar manner, M. tuberculosis reference strain Erdman was compared to a clinical isolate from an individual working with that strain. These isolates had identical DNA fingerprints which were distinct from all other isolates, verifying laboratory-acquired infection. Chromosomal DNA fingerprint patterns produced with IS6110 are excellent stain-specific markers for the epidemiologic study of tuberculosis.

‣ Epidemiologic study design for investigating respiratory health effects of complex air pollution mixtures.

Dockery, D W
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /12/1993 Português
Relevância na Pesquisa
47.103745%
Epidemiologic studies of the respiratory health effects of air pollution are intrinsically difficult because exposure is common, expected effects at concentrations found in developed countries are weak, random misclassification of exposure is common, and the respiratory health indicators have multiple etiologies. Exposures to air pollutants also are multidimensional, generally consisting of a mixture of gases and particles. In this paper, epidemiologic study designs are described, and their potential for evaluating effects of complex pollutant mixtures are discussed. Power to detect the independent effects of individual pollutants in a complex pollutant mixture or to measure their interactions is in general very weak unless the study is specifically designed to test such hypotheses. However, with innovative and creative design, the independent and joint effects of multiple pollutants should be estimable in epidemiologic studies.

‣ Review of epidemiologic study results of vinyl chloride-related compounds.

Apfeldorf, R; Infante, P F
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /10/1981 Português
Relevância na Pesquisa
46.78937%
Epidemiologic study results addressing the carcinogenicity of six compounds related to vinyl chloride (vinylidene chloride, trichloroethylene, perchloroethylene, carbon tetrachloride, ethylene dibromide and epichlorohydrin) are reviewed. The study results suggest an increased carcinogenic risk among workers exposed to epichlorohydrin and to dry cleaning and degreasing solvents. Although several studies report no significant excess of cancer mortality, an evaluation of the design of these investigations demonstrates that these negative cohort studies consisted of populations of insufficient sample size and latency to permit any meaningful conclusions regarding carcinogenic risk. Therefore, experimental studies must be relied upon to determine whether several of these substances pose a potential carcinogenic risk to humans. Available evidence indicates that all of these substances have demonstrated a carcinogenic response in experimental animals and most are mutagenic in experimental test systems.

‣ Current view of epidemiologic study designs for occupational and environmental lung diseases.

Tager, I B
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /08/2000 Português
Relevância na Pesquisa
47.18488%
Epidemiologic studies long have played a role in the understanding of the effects of the general environment and various occupational exposures on the occurrence of acute and chronic diseases of the lung. This article is an overview of epidemiologic study designs that have particular relevance to studies of environmental and occupational lung disease. The application of times-series designs in the context of epidemiologic studies is discussed, as such designs have become widely used in studies of health effects ambient air pollution. The article emphasizes recent developments in the application of case-control study designs, many of which have had particular applications in epidemiologic studies related to environmental and occupational lung disease. These case-control designs offer efficient and valid alternatives for studies that in the past might have been conducted as more costly and time-consuming cohort studies.

‣ An Epidemiologic Study of 100 Cases of Toxoplasmic Uveitis: Implications for Diagnosis and Prevention

Chodos, Joel B.; Habegger-Chodos, Hedwige E.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 09/03/1963 Português
Relevância na Pesquisa
46.735986%
An epidemiologic study of 100 patients with active chorioretinitis, positive Sabin-Feldman methylene-blue dye-test, and favourable response to antitoxoplasmic drugs (spiramycin) was undertaken to establish a basis for rapid clinical diagnosis and institution of preventive measures for toxoplasmic uveitis. Eighty-two of the 100 patients, but only 19 of 100 controls, gave positive histories of exposure to likely sources of toxoplasmosis, such as hunting and handling of wild game, ingestion of raw meat, etc. Seventy-six of these 82 patients had positive toxoplasmin skin tests, but all subsequently had positive dye-tests. The important practical conclusion was reached that all cases with active chorioretinitis, positive toxoplasmin skin test, or history of exposure to known reservoirs of toxoplasmosis should be treated immediately, as dye-tests in such cases will almost invariably be positive. This clinical approach greatly improves the visual prognosis of toxoplasmic chorioretinitis, since specific therapy need not be delayed for several weeks until the result of the dye-test is known.

‣ Diagnostic Studies of Temporomandibular Disorders: Challenges From an Epidemiologic Perspective

Dworkin, Samuel F.; LeResche, Linda; Von Korff, Michael R.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em //1990 Português
Relevância na Pesquisa
46.828687%
Adequate data on the incidence, prevalence, natural history, and clinical course of temperomandibular disorders (TMD) and other chronic pain conditions are largely lacking, though the need to derive such basic data is recognized by clinicians, researchers, and public health agencies. This paper discusses challenges to the epidemiologic study of TMD diagnosis. These challenges include:

‣ Relationship Between Urinary Sodium and Potassium, and Arterial Blood Pressure: An Epidemiologic Study

Miller, George Daniel
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /01/1984 Português
Relevância na Pesquisa
46.735986%
An epidemiologic study was conducted to ascertain the relationship between urinary sodium and potassium, and arterial blood pressure in normal, nonhospitalized adults. Random samples of 1,939 adult residents, 35 to 54 years of age, of Savannah, Georgia; Hagerstown, Maryland; and Pueblo, Colorado, were interviewed and examined. Arterial blood pressures were taken with a standardized zero-muddler in a standard fashion by a specially trained, experienced nurse. Casual urine specimens were collected and analyzed for their sodium and potassium content. The relationship between urinary sodium potassium and the sodium-to-potassium ratio and arterial blood pressure was calculated. Systolic and diastolic pressure increased with increasing levels of urinary sodium and the sodium-to-potassium ratio, and decreased with increasing levels of urinary potassium. The data suggest that dietary potassium provides some protection against the hypertensive effects of dietary sodium in humans as in animals.

‣ The role of anxious and hyperthymic temperaments in mental disorders: a national epidemiologic study

KARAM, ELIE G.; SALAMOUN, MARIANA M.; YERETZIAN, JOUMANA S.; MNEIMNEH, ZEINA N.; KARAM, AIMEE N.; FAYYAD, JOHN; HANTOUCHE, ELIE; AKISKAL, KAREEN; AKISKAL, HAGOP S.
Fonte: Masson Italy Publicador: Masson Italy
Tipo: Artigo de Revista Científica
Publicado em /06/2010 Português
Relevância na Pesquisa
46.983984%
Temperament has been demonstrated clinically to be linked to mental disorders. We aimed to determine the possible role of temperament in mental disorders in a national epidemiologic study. A nationally representative sample of adults (n=1320) was administered the Lebanese-Arabic version of the Temperament Evaluation of the Memphis, Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A), and the Arabic CIDI 3.0, as part of the LEBANON study. The association among temperaments and DSM-IV mood, anxiety, and impulse control disorders was assessed. The anxious temperament was shown to be a robust predictor of most disorders, especially within the anxiety and depressive clusters. The hyperthymic temperament had a uniquely protective effect on most mental disorders, with the exception of separation anxiety, bipolar, substance abuse and impulse control disorders. These effects were moderated by age and education. Temperaments, previously largely neglected in epidemiologic studies, could play a major role in the origin of mental disorders.

‣ Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era

Morton, Lindsay M; Cerhan, James R; Hartge, Patricia; Vasef, Mohammad A; Neppalli, Vishala T; Natkunam, Yasodha; Dogan, Ahmet; Dave, Bhavana J; Jain, Smrati; Levy, Ronald; Lossos, Izidore S; Cozen, Wendy; Davis, Scott; Schenk, Mary Jean; Maurer, Matthew J
Fonte: e-Century Publishing Corporation Publicador: e-Century Publishing Corporation
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
46.78937%
Gene expression profiling studies have distinguished diffuse large B-cell lymphomas (DLBCLs) by cell of origin, with distinct pathogenetic mechanisms and prognosis. We attempted to identify DLBCL molecular subtypes in an epidemiologic study of 214 DLBCL patients diagnosed during 1998-2000 with archival tissues to investigate etiology. Immunohistochemical staining for CD10, BCL6, LMO2, MUM1/IRF4, and BCL2 and fluorescence in situ hybridization for t(14;18) were conducted, with ≥93% blinded duplicate agreement. CD10, LMO2, and BCL2 expression was similar to previous reports (32%, 44%, and 44% of DLBCLs, respectively), but BCL6 and MUM1/IRF4 expression was lower than expected (29% and 5%, respectively). We classified 112/214 (52%) cases as germinal center B-cell-like DLBCL (GCB-DLBCL; Hans et al., Blood 2004; CD10+ or CD10-/BCL6+/MUM1-), with no difference in prognosis compared with non-GCB-DLBCL (Cox regression, P=0.48). Comparing other GCB correlates, LMO2 expression and t(14;18) were more common but not exclusive to GCB-DLBCL as defined in our study, whereas BCL2 expression did not differ between DLBCL molecular subtypes. We could not confidently identify patients with GCB-DLBCL using these immunohistochemistry-based markers on archival tissues.

‣ Achalasia in Korea: An Epidemiologic Study Using a National Healthcare Database

Kim, Eunkyung; Lee, Hongsub; Jung, Hye-kyung; Lee, Kwang Jae
Fonte: The Korean Academy of Medical Sciences Publicador: The Korean Academy of Medical Sciences
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
47.016836%
Owing to the rarity of the disease, epidemiologic information on achalasia is limited. This study aimed to investigate the epidemiology and treatment patterns of achalasia in the population of Korea using a national healthcare database. The diagnostic code K22.0 of the International Classification of Diseases was used to identify cases of achalasia between 2007 and 2011. Treatment modalities for achalasia were identified using the electronic data interchange codes Q7642 or Q7641 for balloon dilation and QA421 or QA422 for esophago-cardiomyotomy. A total of 3,105 patients with achalasia (1,447 men; mean age, 52.5 yr) were identified between 2007 and 2011, indicating a prevalence of 6.29/100,000 (95% confidence interval [CI], 4.94-7.66) during this 5-yr period. A total of 191 incident cases of achalasia (82 men; mean age, 49.5 yr), which were not diagnosed as achalasia in the previous 4 yr, were detected in 2011, indicating an incidence of 0.39/100,000 (95% CI, 0.15-0.63) for that year. During the study period, balloon dilation therapy was performed a total of 975 times in 719 patients, and surgical esophago-cardiomyotomy was performed once per patient in 17 patients. This is the first population-based epidemiologic study of achalasia in Korea.

‣ Bladder Exstrophy: An Epidemiologic Study From the International Clearinghouse for Birth Defects Surveillance and Research, and an Overview of the Literature

SIFFEL, CSABA; CORREA, ADOLFO; AMAR, EMMANUELLE; BAKKER, MARIAN K.; BERMEJO-SÁNCHEZ, EVA; BIANCA, SEBASTIANO; CASTILLA, EDUARDO E.; CLEMENTI, MAURIZIO; COCCHI, GUIDO; CSÁKY-SZUNYOGH, MELINDA; FELDKAMP, MARCIA L.; LANDAU, DANIELLE; LEONCINI, EMANUELE; LI
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
46.78937%
Bladder exstrophy (BE) is a complex congenital anomaly characterized by a defect in the closure of the lower abdominal wall and bladder. We aimed to provide an overview of the literature and conduct an epidemiologic study to describe the prevalence, and maternal and case characteristics of BE. We used data from 22 participating member programs of the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR). All cases were reviewed and classified as isolated, syndrome, and multiple congenital anomalies. We estimated the total prevalence of BE and calculated the frequency and odds ratios for various maternal and case characteristics. A total of 546 cases with BE were identified among 26,355,094 births. The total prevalence of BE was 2.07 per 100,000 births (95% CI: 1.90–2.25) and varied between 0.52 and 4.63 among surveillance programs participating in the study. BE was nearly twice as common among male as among female cases. The proportion of isolated cases was 71%. Prevalence appeared to increase with increasing categories of maternal age, particularly among isolated cases. The total prevalence of BE showed some variations by geographical region, which is most likely attributable to differences in registration of cases. The higher total prevalence among male cases and older mothers...

‣ Epidemiologic study design for investigating respiratory health effects of complex air pollution mixtures.

Dockery, Douglas W.
Fonte: Harvard University Publicador: Harvard University
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
57.136597%
Epidemiologic studies of the respiratory health effects of air pollution are intrinsically difficult because exposure is common, expected effects at concentrations found in developed countries are weak, random misclassification of exposure is common, and the respiratory health indicators have multiple etiologies. Exposures to air pollutants also are multidimensional, generally consisting of a mixture of gases and particles. In this paper, epidemiologic study designs are described, and their potential for evaluating effects of complex pollutant mixtures are discussed. Power to detect the independent effects of individual pollutants in a complex pollutant mixture or to measure their interactions is in general very weak unless the study is specifically designed to test such hypotheses. However, with innovative and creative design, the independent and joint effects of multiple pollutants should be estimable in epidemiologic studies.

‣ Epidemiologic study of anisometropia in students of Natal, Brazil; Estudo epidemiológico da anisometropia em estudantes da cidade de Natal, Brasil

Garcia, Carlos Alexandre de Amorim; Dantas, Erymar de Araújo; Souza, Araken Britto de; Uchoa, Raquel Araújo Costa; Oréfice, Fernando
Fonte: Universidade Federal do Rio Grande do Norte Publicador: Universidade Federal do Rio Grande do Norte
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
47.03909%
To perform an epidemiologic study in students in Natal/Brazil,with relation to refractional anisometropia, evaluating criteria such as: gender, age, and association with strabismus and amblyopia. Methods: A study of 1,024 students randomly selected from several districts of Natal/Brazil was undertaken by the Department of Ophthalmology of the Federal University of Rio Grande do Norte (UFRN), observing the following criteria of ≥ 2 spherical or cylindrical diopter refractional anisometropia relating it to sex, age, association with strabismus, amblyopia and anisometropia classification. Results: We found a prevalence of 2% (N=21) anisometropia in the students. The female gender predominated with 81% (N=17). In students with anisometropia, we observed an association with strabismus in 9.5% of cases (N=2), both with exotropia. The association of anisometropia with amblyopia occurred in 47.6% of the cases (N=10), with 8 cases of unilateral amblyopia and 2 cases of bilateral amblyopia. Conclusions: There was a predominance of anisometropia in females, and an increased prevalence of strabismus and amblyopia in students with anisometropiaTo perform an epidemiologic study in students in Natal/Brazil, with relation to refractional anisometropia...

‣ Measuring Disease Frequency in the Marshfield Epidemiologic Study Area (MESA)

Greenlee, Robert T.
Fonte: Marshfield Clinic Research Foundation Publicador: Marshfield Clinic Research Foundation
Tipo: Artigo de Revista Científica
Publicado em /10/2003 Português
Relevância na Pesquisa
46.735986%
The Marshfield Epidemiologic Study Area (MESA) is a rare resource for population-based health and medical research developed at Marshfield Clinic Research Foundation. Because of high population coverage and health event capture, MESA is particularly useful for determining the frequency of disease in the general population. A substantial proportion of MESA-based publications appearing in the peer reviewed literature have reported incidence or prevalence rates of disease or disease-related factors. This paper reviews the first 10 years of MESA's support of meaningful inquiry into the frequency of disease occurrence, and briefly reports on the data and methods used for such calculations using selected chronic diseases as examples. Limitations of MESA estimates are discussed as are alternate methods. Compared to limited data published for the selected conditions, occurrence rates in MESA based on diagnostic codes and general validation rules only appear somewhat high, although the observed temporal trends and relationships with demographics are consistent. Rich clinical data sources are available to be linked with MESA to improve the specificity of case ascertainment, as is typically done for disease-specific publications from MESA.